MSK path CIS Flashcards

1
Q

if you look at tissue of guillain barre

A

onion bulbing– myelin degeneration

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2
Q

onion skinning in spinal tumor in child

A

ewing

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3
Q

angulation on muscle biopsy

A

atrophy of type II fibers

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4
Q

what can cause atrophy type II fibers

A

DM
guillain barre
hyper and hypothyroid
corticosteroid myopathy

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5
Q

what can cause burning tingling sensations on bottom of feet

A

toxic peripheral neuropathy

chemo drugs for example

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6
Q

median nerve compression

A

thumb, index, middle and part of ring finger

carpal tunnel

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7
Q

heliotrope rash and periorbital edema

A

dermatomyositis

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8
Q

what would confirm Dx dermatomyositis

A

gottron papules

inflammation– perifascicular

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9
Q

Dx of multiple myeloma

A

bone marrow Bx

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10
Q

small teeth
blue sclera
broken bones in infant

A

ostegenesis imperfecta
Type I collagen
deaf- underdeveloped ossicles in ear

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11
Q

what is thinning of bone

A

osteopenia

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12
Q

what can cause osteomalacia

A

vit D deficiency

hyperPTH

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13
Q

difference osteoid ostemoa and osteblastoma

what relieves these

A

osteoblastoma are bigger

aspirin

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14
Q

osteosarcomas arise where in bone

A

metaphysis

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15
Q

codmans triangle means what

A

aggressive

pushing into periosteum

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16
Q

bone outgrowth covered by cartilage

A

osteochondroma

17
Q

ollier disease

A

many enchondromas

18
Q

XR shows metaphysis with floculent material

blue on histo– cartilagenous

A

chondrosarcoma

19
Q

chinese characters

A

fibrous dysplasia

20
Q

saber leg

A

bowing

fibrous dysplasia

21
Q

polyostotic fibrous dysplasia

A

multiple procedures to correct fractures

22
Q

bone growing so fast see onion skinning or starbusrt effect

A

ewings

23
Q

PAS stains what

A

glycogen

24
Q

PNET

A

rossetting

25
Q

bubble looking in bones with fluid fluid levels

A

aneurysmal bone cyst

26
Q

granulomatous lesion

A

rheumatoid nodules

27
Q

rheumatoid nodules most commonly where

A

elbow

28
Q

cross striations in skel muscle

A

scrap cell

rhabdo