MSK path CIS Flashcards

1
Q

if you look at tissue of guillain barre

A

onion bulbing– myelin degeneration

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2
Q

onion skinning in spinal tumor in child

A

ewing

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3
Q

angulation on muscle biopsy

A

atrophy of type II fibers

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4
Q

what can cause atrophy type II fibers

A

DM
guillain barre
hyper and hypothyroid
corticosteroid myopathy

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5
Q

what can cause burning tingling sensations on bottom of feet

A

toxic peripheral neuropathy

chemo drugs for example

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6
Q

median nerve compression

A

thumb, index, middle and part of ring finger

carpal tunnel

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7
Q

heliotrope rash and periorbital edema

A

dermatomyositis

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8
Q

what would confirm Dx dermatomyositis

A

gottron papules

inflammation– perifascicular

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9
Q

Dx of multiple myeloma

A

bone marrow Bx

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10
Q

small teeth
blue sclera
broken bones in infant

A

ostegenesis imperfecta
Type I collagen
deaf- underdeveloped ossicles in ear

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11
Q

what is thinning of bone

A

osteopenia

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12
Q

what can cause osteomalacia

A

vit D deficiency

hyperPTH

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13
Q

difference osteoid ostemoa and osteblastoma

what relieves these

A

osteoblastoma are bigger

aspirin

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14
Q

osteosarcomas arise where in bone

A

metaphysis

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15
Q

codmans triangle means what

A

aggressive

pushing into periosteum

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16
Q

bone outgrowth covered by cartilage

A

osteochondroma

17
Q

ollier disease

A

many enchondromas

18
Q

XR shows metaphysis with floculent material

blue on histo– cartilagenous

A

chondrosarcoma

19
Q

chinese characters

A

fibrous dysplasia

20
Q

saber leg

A

bowing

fibrous dysplasia

21
Q

polyostotic fibrous dysplasia

A

multiple procedures to correct fractures

22
Q

bone growing so fast see onion skinning or starbusrt effect

23
Q

PAS stains what

24
Q

PNET

A

rossetting

25
bubble looking in bones with fluid fluid levels
aneurysmal bone cyst
26
granulomatous lesion
rheumatoid nodules
27
rheumatoid nodules most commonly where
elbow
28
cross striations in skel muscle
scrap cell | rhabdo