MSK Histology Flashcards

Dr P Felts

1
Q

describe a skeletal muscle cell

A

striated
unbranched
multinucleated

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2
Q

what is the cell membrane in a skeletal muscle cell also called?

A

sarcolemma

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3
Q

what are the bundles that muscle fibres are grouped into called?

A

fascicle

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4
Q

what is the connective tissue that covers a single muscle fibre called?

A

endomysium

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5
Q

what is the connective tissue that covers a single fascicle called?

A

perimysium

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6
Q

what is the connective tissue that covers the muscle as a whole called?

A

epimysium

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7
Q

describe the organisation of the muscle

A

muscle fibre contain many myofibrils with each consisting of many sarcomeres

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8
Q

what is the unit of contraction in muscle cells?

A

sarcomere

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9
Q

what does the sarcomere extend from and to?

A

z line

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10
Q

what does a motor unit consist of?

A

one motor neurone and all of the muscle fibres that it innervates

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11
Q

what does a fewer number of muscle fibre in a motor unit result in?

A

a finer control of movement

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12
Q

what is the special name of synapse in muscles?

A

neuromuscular junction

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13
Q

how many types of skeletal muscle fibre are there? name them.

A

3

type I
type IIA
type IIB

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14
Q

describe type I

A

slowly contracting fibres

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15
Q

is cartilage permeable?

A

yes

bone is not permeable

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16
Q

what are the cells found in cartilage called?

A

chondrocytes (chondroblasts when immature

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17
Q

what is the name of the extracellular metric chondrocytes live in?

18
Q

what type of collagen is most common in cartilage?

A

type II cartilage

19
Q

name the 3 types of cartilage

A

hyaline
elastic
fibrocartilage

20
Q

what is the most common type of cartilage?

A

hyaline

blue-white in colour

21
Q

what colour is elastic cartilage?

A

light yellow - flexible

22
Q

what colour is elastic cartilage?

A

light yellow - flexible

23
Q

describe fibrocartilage

A

hybrid of tendon and hyaline cartilage
type I collagen
appears white

24
Q

name the 2 types of bone

A

cortical bone

cancellous/trabecular bone

25
where on the bone is cortical bone seen?
outer shell | shaft
26
what is the other word of the shaft of the bone?
diaphysis
27
where does cancellous/trabecular bone occupy?
ends of bone
28
what is the other word for end of bone?
epiphyses
29
what are the living cells contained in cortical bone called?
osteocytes
30
cortical bone penetrated by blood vessels forming what?
canals
31
cortical bone penetrated by blood vessels forming what?
canals
32
what are the lines that are often visible surrounding the osteon termed?
cement lines
33
name the cell: located on bone surfaces, for example under the periosteum, these cells serve as a pool of reserve osteoblasts
Osteoprogenitor cells
34
name the cell: bone forming cells found on the surface of developing bone. They have plentiful RER and prominent mitochondria
osteoblasts
35
name the cell: a bone cell trapped within the bone matrix
osteocytes
36
name the cell: large (up to 40µm or more) multinucleated cells. They are found on the surface of bone and are responsible for bone resorption
osteoclasts
37
what is the collective term given to the components that osteoblasts secrete?
osteoid
38
Younger osteons often partially obliterate older osteons true or false?
true
39
what is the name of the bone that is laid down following a break?
woven bone
40
how does woven bone differ to normal lamellar bone?
collagen is laid in haphazard fashion in comparison to one direction in lamellar bone woven bon dis not as strong as lamellar bone