Morphology of inflammation

Question 1

Duration of inflammation

Answer 1

-Peracute- really fast, prominent vascular changes
-Acute- 4-6 hrs and can go on for several days
-Subacute-Several days after, mixed cellular response
-Chronic-Several days to weeks, collagen present, mononuclear cells and fibrosis

Question 2

Serous inflammation

Answer 2

-Edema
-Accumulation of serum like fluid
-Dilution of offending agent
-excessive fluid can interfere with tissue function

Question 3

Catarrhal inflammation

Answer 3

-Large amounts of mucus
-Protection of mucosal surfaces
-Dilution of offending agent

Question 4

Fibrinous inflammation

Answer 4

-Large amounts of fibrin
-Protect underlying tissue
-Prevent blood loss
-Scaffold for subsequent fibrous tissue

Question 5

Purulent inflammation

Answer 5

-Large amount of neutrophils
-Defend against infections agents
-Produce pro-inflammatory agents
-Sometimes interfere with tissue function

Question 6

Abscess

Answer 6

Localized and confined accumulation of neutrophils and liquefied debris
-Fibrous capsule (means chronic)
-Walled off from normal adjacent tissue

Question 7

Hemorrhagic inflammation

Answer 7

-Large amounts of hemorrhage at site
-From vascular injury
-Arise quickly
-Associated with more sever inflammation

Question 8

Eosinophilic inflammation

Answer 8

-Lots of eosinophils
-Mediate local or systemic hypersensitivity reactions

Question 9

Lymphocytic inflammation

Answer 9

-Lymphocytes
-Immunological response to antigens
-Important for chronic inflammation

Question 10

Granulomatous inflammation

Answer 10

-Lots of macrophages
- Associated with chronic, difficult to manage inflammatory agents
-Can form solid masses and interfere with tissue function

Question 11

Granuloma

Answer 11

-Central core of caseous necrosis
-Zone of epithelioid macrophages and giant cells
-Zone of lymphocytes
-Outer zone of fibroblasts and collagen