Module 7 breast cancer Flashcards
screening options (5)
mammogram MRI clinical/self breast exam genetic testing breast US
USPSTF women aged 50-74
biennial screening mammography
USPSTF women aged 40-49
Women who place a higher value on the benefit than the harms may choose to begin biennial screenings
USPSTF women >75
current evidence insufficient regarding mammograms
USPSTF all women digital breast exam
current evidence is insufficient
USPSTF women with dense breasts
evidence insufficient for screening with US, MRI, digital exam with otherwise negative mammogram
false positive mammogram
younger women and in women with dense breasts
women taking estrogen
Dx of ductal carcinoma in situ: non-invasive tumor
False negative mammogram
can miss up to 20% of cancers
more common in women with dense breasts, therefore more common in younger women
Breast MRI
not recommended as a routine screening
- higher risk false +
- more expensive
- not as available
ACS recommends:
- all women with a >20% risk have a yearly mammogram AND MRI
- women with 15-20% risk should consider MRI
Factors that increase breast cancer risk
BRCA1/2 gene 1st degree relative with BRCA1/2 lifetime risk of breast cancer 20-25% - risk assessment tools Radiation therapy to chest Another type of cancer between ages 10-30 Genetic disease: self or 1st degree relative - Li-Fraumeni - Cowden syndrome - Bannayan-Riley-Ruvalcaba syndrome
Clinical breast exam and self exam
no longer addressed by USPSTF
not recommended by ACS