Mitosis Flashcards

1
Q

After replication of chromosomes, each replicated chromosome consists of two separate sister ______

A

chromatids

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2
Q

During the division process, a mitotic ___________ is formed so that the chromosomes are divided equally between the 2 new daughter cells

A

spindle apparatus

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3
Q

After cell division the 2 new daughter cells should have the same ______ and ______ as the original parent cell

A

number of chromosomes same genetic info

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4
Q

In mitosis, a diploid 2n cell gives rise to two new _____ cells

A

diploid

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5
Q

What are the 5 stages of mitotic nuclear division?

A
Prophase
Pro-metaphase
Metaphase
Anaphase
Telophase 
(PPMAT)
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6
Q

After nuclear division is complete, the cell contents divide. This process is known as _______

A

cytokinesis

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7
Q

During nuclear divisions, chromosomes are separated by __________

A

microtubules

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8
Q

What are the three types of microtubles?

A

Astral
Kinetochore
Polar

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9
Q

Interphase: Prior to mitosis, the ___________ and the _________ have already replicated

A

chromosomes

centrosomes

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10
Q

each centrosome contains a pair of ________

A

centrioles

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11
Q

What happens at prophase?

A

Chromosomes start to condense
Sister chromatids become visible
mitotic spindle starts to form OUTSIDEthe nucleus

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12
Q

What happens at pro-metaphase?

A

Nuclear envelope has broken into small vesicles
spindle microtubles enter nuclear region
microtubles attach kinetechores

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13
Q

What happens at metaphase?

A

Chromosomes held in tension at the metaphase plate, halfway between poles
Chromosomes are attached to kinetochore microtubles

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14
Q

What happens at anaphase?

A

Sudden separation of the sister kinetochores
Polar microtubles lengthen
Kinetochore microtubules shorten

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15
Q

What happens at telophase?

A

Nuclear envelope starts to reform
Chromosomes expand and decondense
Cytoplasm constricts
After cytokinesis, cells return to interphase

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16
Q

What effect does Colchicine (used in the treatment of gout) have on the effect of mitosis?

A

prevents polymerisation of microtubles

17
Q

What effect do Vinestine and Vinblastine have on mitosis?

A

Prevent polymerisation of microtubles

18
Q

What effect does Taxol have on mitosis?

A

binds and stabilises microtubles