Kidney and drug excretion Flashcards
Kidneys receive 20% of cardiac output. True or false?
True
What is the role of the kidneys?
Elimination of nitrogen-containing waster e.g urea and uric acid
Maintain water, ionic and pH balance in body fluids
Central role in filtering blood and forming urine
Production of hormones
Elimination of drugs and metabolites
Which region of the kidney filters blood?
glomerular
Where is the renal pyramid found?
In the medulla
The nephron represents a functional unit of the kidney. True or false?
True
What does the renal corpuscle consist of?
Bowman’s capsule
Glomerulus
What are the functions of the renal corpuscle?
Filter the blood (glomerular filtration)
After blood has been filtered, the remaining blood leaves the glomerulus via ___________
efferent arterioles
The renal copuscle has two arteries - one going in and one going out. True or false?
True
What is the advantage of using inulin?
There isn’t any present in the body unless it is administered so it gives a good indication for GFR
What factors influence GFR?
Body size
Gender
Age
GFR in men is higher than women. True or false?
True
Where does glomerular filtration take place?
From the glomerular capillaries to the Bowman’s capsule
Glomerular filtration is an active process. True or false?
False - it is a passive, non-selective process
How does tubular secretion work?
Selective transport of molecules from the peritubular fluid to the lumen of renal tubules - facilitates excretion