Cell adhesion and cell junctions Flashcards

1
Q

What are the four main tissue types?

A

Epithelia
Connective
Nervous
Muscle

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2
Q

As you move from epithelial tissue to connective tissue, what happens to the amount of collagen?

A

It increases

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3
Q

As you move from epithelial tissue to connective tissue, what happens to the amount of cells?

A

decrease

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4
Q

As you move from the epithelial tissue to connective tissue, what happens to the amount of matrix?

A

It increases

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5
Q

In epithelial tissue, extracellular matrix is only found at the bottom of the basal layer. True or false?

A

True

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6
Q

What are the three major groups that cell junctions can be classified into?

A

Occluding junctions
Anchoring junctions
Communicating junctions

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7
Q

Tight junctions are an example of which major group of cell junctions?

A

Occluding junctions

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8
Q

Actin filaments e.g. adhesion belt is an example of which major group of cell junction?

A

Anchoring junctions

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9
Q

What are cadherins?

A

Calcium dependent adherent proteins

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10
Q

Actin filaments and adhesion belt are important in developmental processes. True or false?

A

True

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11
Q

In intermediate filaments, what is the role of hemi-desmosomes?

A

Hold cells onto the basal lamina

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12
Q

Intermediate filaments are an example of which major group of cell junctions?

A

Anchoring junctions

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13
Q

In intermediate filaments, what is the role of desmosomes?

A

Hold cells together

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14
Q

Gap junctions are an example of which major group of cell junctions?

A

Communicating junctions

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15
Q

Gap junctions allow the free passage of molecules less than ______ MWt

A

5000

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16
Q

A connexon in a gap junction is composed of how many subunits?

A

6

17
Q

When is the channel formed by 2 connexons closed?

A

When there is a high conc of calcium or when there is a low pH

18
Q

When is the channel formed by 2 connexons open?

A

When there is a low conc of calcium or when there is a high pH