Dissolution of tablet to bloodstream

Question 1

What is mass transfer?

Answer 1

The net movement of mass from one location to another

Question 2

What is the driving force?

Answer 2

The difference of chemical potential i.e. difference in concentrations

Question 3

Diffusion explains mass transfer in absence of additional _____

Answer 3

forces

Question 4

What is the unit for diffusion coefficient?

Answer 4

area/time

Question 5

Small molecules diffuse slower than large molecules. True or false?

Answer 5

False

Question 6

Which factors influence membrane permeability?

Answer 6

Diffusion coefficient
Partition coefficient
thickness of membrane

Question 7

Ideally, you want a drug with a high _____ and a high ______

Answer 7

permeability

solubility

Question 8

The rate of absorption of a weak acid is often higher in the intestine than in the stomach. True or false?

Answer 8

True

Question 9

The residence time in the small intestine is longer than in the stomach. True or false?

Answer 9

True

Question 10

Ions in solution can pair with ______ ions which will help them to dissolve

Answer 10

counter ions

Question 11

Diffusion reflects the change of concentration of drug over time. True or false?

Answer 11

True