Midterm - Lecture 8 Flashcards

1
Q

What are the normal phosphorus blood levels?

A

4-8 mg/dl for most species

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2
Q

What can cause low phosphorus blood levels?

A

vitamin D deficiency or dietary P inadequacy

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3
Q

What are plant sources of phosphate usually tied up as?

A

phytate phosphorus

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4
Q

How much of cereals, legumes, and other points are tied up as phytate phosphorus?

A

60-70 %

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5
Q

How well can monogastrics digest phytate phosphorus?

A

not very well 0-40 %
high in wheat
0% in corn

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6
Q

Why can ruminants make use of phytate phosphorus?

A

because their microbes in the rumen can break it down

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7
Q

How does the saliva of ruminants play a role in phosphorus digestion?

A

the salivary secretions can remove 30-90 g of phosphorus from the extracellular phosphorus pool each day, then the phosphorus secreted is recovered by intestinal resorption

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8
Q

What happens when ruminants stop chewing?

A

lower rumen pH - less bugs (bacteria)- dead cow

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9
Q

What happens with downer cows?

A

when plasma P is below 1.5mg/100 ml
unable to stand
NOT due to dietary phosphorus deficiency

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10
Q

What is the cause of rickets?

A

diet fails to have adequate P to support bone growth

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11
Q

What animals usually get rickets?

A

mostly monogastrics fed plant diets where phosphorus is tied up by phytate

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12
Q

What is osteomalacia?

A

adult rickets, the failure of osteoid to mineralize during bone remodeling

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13
Q

What are normal blood magnesium levels?

A

1.8-2.4 mg/dl

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14
Q

How can blood magnesium levels be lowered?

A

by increasing renal excretion of Mg

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15
Q

What are the major functions of magnesium?

A
  • cofactor to activate many enzymes involved in catabolism and anabolism
  • extracellular Mg is vital to maintenance of normal nerve and muscle cell stability
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16
Q

What is hypomagnesemia?

A

low blood levels of magnesium that cause tetany

17
Q

What is hypermagnesemia?

A

high blood levels of magnesium that causes slow reaction time

18
Q

How is magnesium absorbed in monogastrics and young ruminants?

A

absorbed from ileum and colon by passive absorption

rare to see deficiency

19
Q

How is magnesium absorbed in ruminants?

A

absorption depends on the Mg concentration in solution in the rumen and the integrity of the rumen Mg active transport mechanism

20
Q

What animals is grass tetany observed in?

A

lactating beef or dairy animals at pasture

21
Q

What are the ion levels observed in grass tetany?

A

low levels of Mg and high levels of K, also low levels of Ca

22
Q

What are the side effects of grass tetany?

A

hyperexcitable nerves- PNS and CNS
muscle tremors
nystagmus
convulsions leading to a coma

23
Q

Is there a role for magnesium in urolithiasis?

A

too mugh Mg causes struvite stones to form in the bladder and block urethra in male cats