Microbiology - Infection CPC Flashcards

1
Q

How does pneumocystis jireovecii pneumonia appear on CT chest?

A

Groundglass opacity
CXR may be fairly normal

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2
Q

How should PCP pneumonia be treated?

A

Co-trimoxazole BD

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3
Q

Which 3 bacteria are people with a B cell immunological defect most susceptible to?

A

Strep
Staph
Haemophilus

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4
Q

Which t2 bacteria are people with a neutrophil immunological defect most susceptible to?

A

Staph
Pseudomonas

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5
Q

Which type of bacteria are people with a complement defect most susceptible to?

A

Neisseria

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6
Q

Which type of virus are people with a B cell immunological defect most susceptible to?

A

Enteroviral encephalitis

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7
Q

Which 3 viruses are people with a T cell immunological defect most susceptible to?

A

CMV
EBV
Varicella

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8
Q

Which 2 fungal infections are people with a T cell immunological defect most susceptible to?

A

PCP
Candidia

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9
Q

Which 2 fungal infections are people with a neutrophil immunological defect most susceptible to?

A

Candida
Aspergillus

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10
Q

What infection are alcoholics more susceptible to than the general population and why?

A

Alcohol also immunosuppresses - they are more at risk of actinomyces lung abscesses

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11
Q

What phrase is pathognemonic for actinomyces abscesses?

A

Basiphilogranules (sulphur granules)

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12
Q

Why are antibiotics not useful in osteomyelitis?

A

They ca’t access necrotic bone that is lacking blood supply

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13
Q

what stain to visualise HIV

A

Grocott-Gomori’s (or Gömöri) methenamine silver stain

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14
Q

what is the most importance part in the treatment of prosthetic joint infections

A

removal of prostheses and debridement

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15
Q

drug of choice for non severe c diff

A

metronidazole PO TDS 400mg 14 days

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16
Q

drug of choice for severe c diff

A

vancomycin 125mg PO QDS 14days
if tachycardia, pyrexic, or failing to respond consider referral to surgeons and gastro

17
Q

c diff is usually associated w what

A

recent history of antibiotic use

18
Q

shortness of breath worsens on exertion in what pneumonia?

A

PCP
spo02 tends to drop on exertion more