MicroBioFinal - LymeDisease

Question 1

disease agent

Answer 1

Barrelia Burgdorferi (underlined)

• spirochete
• gram negative
• motile (flagella)
• 40% plasmid dna
• binary fission

Question 2

transmission

Answer 2

biological vector: black legged tick(deer tick)

• must bite for atleast 48 hrs to transmit bacteria
• CDC says it cannot be transmitted through sexual activity
• replication occurs in bone, tendon, nerves, joints, etc.

Question 3

symptoms

Answer 3

3 week incubation

• early localized - target lesions, stiff neck
• early disseminated - several weeks; systemic; multiple target lesions, cardiac problems, neurological problems, etc.
• late lyme - joint problems, cardiac problems, neuropathies, etc

Question 4

detection

Answer 4

• early localized - target lesion
• early disseminated - look for seroconversion (lyme antibodies)
• late lyme - need dna fingerprint at this point

Question 5

treatment

Answer 5

• early localized - Doxycycline: 21 days; attacks ribosomes; Amoxicilin: if pregnant; 21 days; attacks cell wall production
• early disseminated - therapies that depend on symptoms
• late lyme - therapies and Doxycline and Amoxicillin; 1 month

Question 6

prevention

Answer 6

• Lymerix Vaccine - actually gave ppl lyme disease; used from 1998-2002
• protective clothing
• deet, teatree oil, natural herbs
• public awareness; check for ticks

Question 7

epidemiology

Answer 7

tick: 2 yr life cycle
- lyme typically spread may, june, july
- early localized and disseminated found in august, september, october