Micro Chapter 38 Flashcards
Which of the following viral diseases is spread via airborne transmission? A) West Nile Fever B) Smallpox C) Common cold D) Hepatitis A
B
The causative agent of both chicken pox and shingles is A) Variola virus B) Influenza C) Varicella-zoster virus D) Rhinovirus
C
Where does latent varicella-zoster virus reside until reactivated?
A) The cytoplasm of T cells
B) Nuclei of the cranial nerves and sensory nerves in the dorsal root ganglia
C) Interstitial spaces between skin cells
D) Retinal cells
B
The worst influenza pandemic on record occurred in A) 1918 B) 1957 C) 1968 D) 1977
A
Influenza virus enters host cells via A) Fusion with the cell membrane B) Injection of a polar tube C) Receptor-mediated endocytosis D) Phagocytosis
C
Influenza viruses are classified into subtypes based on which of the following characteristics A) Membrane surface glycoproteins B) Hemagglutinin (HA) spikes C) Neuraminidase (NA) spikes D) All of the above
D
What is the function of influenza hemagglutinin and neuraminidase spikes?
A) Assist in viral lysis
B) Aid in genome replication
C) Aid in viral attachment and virulence
D) Assist in capsid assembly
C
Which of the following events results in influenza epidemics and pandemics?
A) Antigenic drift or accumulation of minor mutations in HA and NA in a single strain of flu virus
B) Antigenic shift or the reassortment of genomes of two or more different strains of flu
C) Loss of HA and NA receptors
D) None of the above
B
Which of the following animals is involved in the transmission of influenza virus? A) Human B) Pig C) Birds D) All of the above
D
The most recent H1N1 influenza pandemic occurred in A) 1918 B) 1968 C) 1977 D) 2009
D
Which strain of flu led to the culling of millions of birds between 2003 and 2008 due to threat of bird-to-human transmission? A) H1N1 B) H2N1 C) H3N2 D) H5N1
D
The antiviral drugs zanamivir (Relenza) and oseltamivir (Tamiflu) combat the flu virus by which of the following mechanisms?
A) Degrading viral DNA
B) Blocking entry of the virus into the host cell
C) Blocking the release of virions from the host cell
D) All of the above
C
Where does the measles virus enter the host?
A) Through a puncture wound in skin
B) Through the intestinal mucosa
C) Through the respiratory tract or the conjunctiva of the eye
D) All of the above
C
The best way to prevent measles is through which of the following methods?
A) Social isolation
B) Water and sewage treatment
C) Use of condoms during sexual activity
D) MMR vaccination in childhood
D
Mumps is spread via A) Saliva and respiratory droplets B) Mosquito bites C) Direct contact D) Fomites
A
Which characteristic is the hallmark of the respiratory syncytial virus (RSV)?
A) Pores in the membranes or respiratory cells
B) Multinucleated masses of fused cells
C) Lysing of alveolar macrophages
D) All of the above
B
Which of the following diseases can lead to fetal death, premature delivery, or congenital heart defects? A) Measles B) Mumps C) Rubella D) Influenza
C
Which of the following groups of viruses is the causative agent of severe acute respiratory syndrome (SARS)? A) Coronaviruses B) Rhinoviruses C) Parainfluenza viruses D) Adenoviruses
A
Which of the following structures on coronaviruses aid in the attachment of virions to host cells? A) Sticky envelope B) Dense cilia C) Neuraminidase spikes D) Large peplomers
D
The initial outbreak of SARS originated in China in A) 1997 B) 2001 C) 2002 D) 2005
C
Global eradication of smallpox was possible because of which of the following features of the disease?
A) Only human hosts are reservoirs
B) There are virtually no asymptomatic carriers
C) The disease has a short period of infectivity
D) All of the above
D
Approximately what proportion of the world's population has not been vaccinated against smallpox and thus vulnerable to the disease? A) 10% B) 25% C) 50% D) 100%
C
The virus that causes which of the following diseases has the potential to be used as a bioweapon? A) Rubella B) Smallpox C) West Nile fever D) HIV
B
Which of the following diseases is caused by a viral pathogen spread via arthropod vector? A) Equine encephalitis B) Smallpox C) Poliomyelitis D) Human parvovirus B19
A
In the United States, cases of West Nile fever peak during which time of the year, corresponding with peak numbers of mosquitoes? A) Spring B) Early summer C) End of summer D) Fall
C
Which of the following is an example of a viral disease spread via direct contact between individuals? A) Measles B) AIDS C) Hepatitis A D) Ebolavirus
B
Which of the following viruses caused a global pandemic in the second half of the 20th Century? A) Hepatovirus B) Vaccinia C) HIV D) Human parvovirus B19
C