Micro Chapter 33 Flashcards

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1
Q
In the human immune system, the first line of defense against any microorganisms or foreign material encountered is known as 
  A) Acquired immunity 
  B) Adaptive immunity 
  C) Specific immune response 
  D) Non-specific immune response
A

D

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2
Q
In the human immune system, resistance to a particular foreign agent, based on repeated exposure to the agent, is known as 
  A) Acquired immunity 
  B) Innate immunity 
  C) Natural immunity 
  D) Non-specific host resistance
A

A

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3
Q
Substances that are recognized by the body as foreign and provoke an immune response are called 
  A) Antibodies 
  B) Antigens 
  C) Cytokines 
  D) White blood cells
A

B

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4
Q
In the immune response, antibodies 
  A) Provoke an immune response 
  B) Bind to specific antigens and inactivate them 
  C) Release inflammatory chemicals 
  D) All of the above
A

B

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5
Q
Which of the following cells function in both innate and adaptive immunity? 
  A) Red blood cells 
  B) White blood cells 
  C) Skin cells 
  D) All of the above
A

B

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6
Q
Thick, closely packed skin cells that are shed to remove microbes are called 
  A) Epithelial cells 
  B) Endothelial cells 
  C) Keratinocytes 
  D) Sweat glands
A

C

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7
Q

The function of lysozyme in mucous membranes performs which of the following functions?
A) Hydrolyzes peptidoglycan
B) Reduces the amount of iron available to microbes
C) Lyses the plasma membrane
D) Damages DNA

A

A

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8
Q

The function of lactoferrin in the mucous membranes is to
A) Hydrolyze peptidoglycan
B) Reduce the amount of iron available to microbes
C) Lyse the plasma membrane
D) Damage DNA

A

B

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9
Q
Which of the following enzymes in the mucous membranes catalyzes the production of superoxide radicals that are toxic to microorganisms? 
  A) Lysozyme 
  B) Lactoferrin 
  C) Lactoperoxidase 
  D) Cryptins
A

C

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10
Q
Which of the following actions is part of the immune response in the respiratory system? 
  A) Coughing and sneezing 
  B) Mucociliary blanket 
  C) Alveolar macrophages 
  D) All of the above
A

D

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11
Q
Which of the following gastrointestinal responses is part of the nonspecific host response? 
  A) Mucociliary blanket 
  B) Peristalsis 
  C) Insulin production 
  D) Decreasing acid production
A

B

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12
Q

Which of the following is TRUE of nonspecific host defenses of the genitourinary tract?
A) Alkaline conditions controls microbial growth
B) Normal microbiota in the kidneys inhibit growth of pathogens
C) Estrogen influences production of glycogen, this is degraded by bacteria into lactic acid
D) All of the above

A

C

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13
Q

Which of the following best describes the structure of defensins?
A) Alpha-helical peptides that lack cysteine amino acid residues
B) Peptides are rich in arginine and cysteine and are disulfide linked
C) Larger peptides enriched for specific amino acids that exhibit regular structural repeats
D) Benzene ring structures

A

B

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14
Q
Antimicrobial peptides produced by normal microbiota are known as 
  A) Cathelicidin 
  B) Defensins 
  C) Histamine 
  D) Bacteriocins
A

D

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15
Q

The complement system performs which of the following functions?
A) Facilitating and enhancing phagocytosis
B) Bridging innate and adaptive immune responses
C) Disposing of immune waste products
D) All of the above

A

D

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16
Q
The coating of microorganisms by serum components, thereby preparing them for recognition and ingestion by phagocytic cells is called 
  A) Agglutination 
  B) Opsonization 
  C) Differentiation 
  D) Apoptosis
A

B

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17
Q
Which of the following complement pathways responds to bacterial lipopolysaccharides (LPS) and results in the formation of the membrane attack complex (MAC)? 
  A) The alternative complement pathway 
  B) The lectin complement pathway 
  C) The classical complement pathway 
  D) All of the above
A

A

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18
Q
Which of the following complement pathways responds to mannose on pathogen surfaces and results in opsonization of pathogens? 
  A) The alternative complement pathway 
  B) The lectin complement pathway 
  C) The classical complement pathway 
  D) All of the above
A

B

19
Q
Which of the following complement pathways responds to bacterial products and results in the formation of antibodies? 
  A) The alternative complement pathway 
  B) The lectin complement pathway 
  C) The classical complement pathway 
  D) All of the above
A

C

20
Q
A soluble protein or glycoprotein released by one cell population to signal between cells is called 
  A) An enzyme 
  B) A cytokine 
  C) A bacteriocin 
  D) None of the above
A

B

21
Q
Which of the following families of cytokines play a central role in the inflammatory response by stimulating cell migration and attracting phagocytic cells and lymphocytes? 
  A) Chemokines 
  B) Hematopoietins 
  C) Interleukins 
  D) Tumor necrosis factor (TNF)
A

A

22
Q

Which of the following is TRUE of leukocytes?
A) Responsible for nonspecific immune response only
B) Originate in a variety of cells throughout the body
C) Capable of differentiating into diverse cells involved in a variety of immune functions
D) All of the above

A

C

23
Q

Granulocytes
A) Differentiate into plasma cells and form antibodies
B) Contain granules that contain reactive substances that kill microbes and enhance inflammation
C) Perform phagocytic activities on microbes
D) Kill foreign cells by lysing membranes

A

B

24
Q
Which of the following granulocytes release vasoactive mediators in the nonspecific immune response? 
  A) Basophils 
  B) Eosinophils 
  C) Neutrophils 
  D) All of the above
A

A

25
Q
Which of the following granulocytes are important in the defense against protozoan and helminth parasites? 
  A) Basophils 
  B) Eosinophils 
  C) Neutrophils 
  D) All of the above
A

B

26
Q
Which of the following granulocytes house lytic enzymes and bactericidal substances? 
  A) Basophils 
  B) Eosinophils 
  C) Neutrophils 
  D) All of the above
A

C

27
Q
Which of the following immune cells bind microbial PAMPs with its PRRs leading to phagocytosis of the microbial cell? 
  A) Granulocytes 
  B) Neutrophils 
  C) Macrophages 
  D) Lymphocytes
A

C

28
Q
Which of the following immune cells is involved in phagocytose antigens and are involved in antigen presentation? 
  A) Mast cells 
  B) Macrophages 
  C) Dendritic cells 
  D) Lymphocytes
A

C

29
Q
Which of the following lymphocytes secretes large quantities of antibodies? 
  A) B cells 
  B) T cells 
  C) Natural killer cells 
  D) All of the above
A

A

30
Q
Which of the following lymphocytes release cytokines to damage and kill microbes? 
  A) B cells 
  B) T cells 
  C) Natural killer cells 
  D) All of the above
A

B

31
Q
Which of the following lymphocytes bind to antibodies and coat infected cells facilitating the antibody-dependent cell-mediated cytotoxicity (ADCC)? 
  A) B cells 
  B) T cells 
  C) Natural killer cells 
  D) All of the above
A

C

32
Q
Which of the following is a primary organ of the immune system? 
  A) Thymus 
  B) Spleen 
  C) Skin-associated lymphoid tissues 
  D) All of the above
A

A

33
Q
Which of the following is a secondary organ of the immune system? 
  A) Thymus 
  B) Bone marrow 
  C) Spleen 
  D) All of the above
A

C

34
Q
B cells mature in the 
  A) Bone marrow 
  B) Thymus 
  C) Spleen 
  D) Lymphoid tissues
A

A

35
Q
T cells mature in the 
  A) Bone marrow 
  B) Thymus 
  C) Spleen 
  D) Lymphoid tissues
A

B

36
Q
What percent of T cells formed in the thymus are selected to become mature T cells? 
  A) 2% 
  B) 10% 
  C) 50% 
  D) 98%
A

A

37
Q
Which of the following secondary lymphoid organs or tissues filters blood and traps blood-borne microorganisms and antigens? 
  A) Lymph nodes 
  B) Lymphoid tissues 
  C) Spleen 
  D) All of the above
A

C

38
Q
Natural killer (NK) cells recognize abnormal cells 
  A) That display major histocompatibility complex (MHC) class I surface molecules 
  B) That contain major histocompatibility complex (MHC) class I surface molecules 
  C) That lack major histocompatibility complex (MHC) class I surface molecules 
  D) None of the above
A

C

39
Q
A specific type of PRRs that function as signaling receptors, bind the host cell nucleus, and initiate appropriate gene expression are called 
  A) PAMPs 
  B) Toll-like receptors (TLRs) 
  C) MHC Class I receptors 
  D) MHC Class II receptors
A

B

40
Q

Lysosomes with reactive nitrogen species (RNSs) work by
A) Increasing oxygen consumption and ATP needed for phagocytosis
B) Blocking cellular respiration and complexing with iron in electron transport proteins
C) Damaging peptidoglycan and cell membranes
D) All of the above

A

B

41
Q

Which of the following events occurs during the acute inflammatory response?
A) Injured tissue cells release chemical signals that activate endothelial cells of nearby capillaries
B) Blood and immune cells are diverted from the site of injury via chemical signaling
C) Cytokine release results in vasoconstriction
D) Inhibition of the pain response occurs

A

A

42
Q

How is a pathogen neutralized or eliminated during the acute inflammatory response?
A) Increased blood flow brings in leukocytes to destroy pathogens
B) Blood leaks into tissue spaces and increases temperature to inhibit microbial growth
C) Fibrin clots form to limit the spread of the microbes
D) All of the above

A

D

43
Q

Which of the following is TRUE of chronic inflammation?
A) Is a rapid and transient process
B) Characterized by a dense infiltration of lymphocytes and macrophages
C) Stimulated by viruses only
D) All of the above

A

B