Metabolism And Electrolytes Flashcards
Define metabolism
The sum of all chemical reactions in the body
Define anabolism
Building larger molecules from smaller ones - this requires ATP
Define catabolism
Breaking down larger molecules to smaller (releases ATP)
Enzymes
“Functional proteins” a chemical catalyst to assist in metabolic reactions
Catalyst
Chemical that reduces the amount of activation energy needed to start a chemical reaction
Coenzymes
Organic nonprotein enzymes are a cofactor for enzymes
- every reactor requires a specific enzyme and require a lot of energy
- ATP <-> ADP, +P +energy
catabolism is known as what
Known as cellular respiration
The three metabolic pathways
PCr -> Creatine phosphate
Anaerobic/short-term
Aerobic/short-term
Creatine phosphate
ADP + CP -> ATP + Cr ATP-PC
Stores limited amounts of ATP and must have a system to to supply quickly
- Resynthesizes ATP from ADP almost instantly
- This is also how Creatine works
Aerobic/long-term examples
Examples: beta oxidation, deamination, Krebs (citric acid) cycle, electron transplant chain
Krebs cycle
This is aerobic, not using oxygen directly and this occurs within the mitochondria.
Fuel = Acetyl CoA
Produces more ATP, NADH2, FADH2, for the ETC/OP. This can then in turn form CO2
What is the rate limiting enzyme for Krebs cycle
Isocitrate dehydrogenase
Anaerobic/short-term
Glycolysis
Anaerobic, with cytoplasm
The net result glucose: 2 ATP, 2 NADH, 2 pyruvate
The net result glycogen: 3 ATP, 2 NADH, 2 pyruvate
Complete aerobic catabolism = 36 ATP
What is the rate limiting enzyme of anaerobic/short-term
Phosphofructokinase
ETC
Aerobic, mitochondria, has a inner membrane
NADH and FADH are oxidized
ATP is phosphorylated (lots of it)
O2 is used directly, and H2O is created