Malignant Kidney Tumours Flashcards
1
Q
Presnetation of renal cell carcinoma?
A
Haematuria Loin pain Loin mass -Pyrexia -Varicocele -Endocrine effects -Mets at Presnetation (25%) -Paraneoplastic hepatic dysfunction syndrome AKA Stauffer syndrome
2
Q
What does Stauffer syndrome present as?
A
Cholestasis/hepatosplenomegaly
3
Q
Associations of RCC?
A
- Middle aged men
- Smoking
- Von-Hippel-Lindau syndrome
- Tuberous sclerosis
4
Q
Investigations of RCC?
A
- USS
- CT chest abdomen, pelvis for staging
- FBC
- RFT & LFT
5
Q
Treatment of small tumour in RCC?
A
- Surveillance in elderly unfit patients
- Ablation techniques in fit elderly patients and selected younger patients
6
Q
Criteria for a small tumour?
A
<3cm
7
Q
Criteria for a large tumour?
A
> 3cm
8
Q
Treatment of a large tumour in RCC?
A
Partial nephrectomy
-Radical nephrectomy
9
Q
Treatment of large TumourSS?
A
Radical nephrectomy (laparoscopic)
10
Q
What is first line treatment for RCC, chemo or radiotheraoy?
A
NEITHER
RCC DOES NOT RESPOND WELL TO CHEMO/RADIO
11
Q
What medications are used to shrink tumours in RCC?
A
Alpha-interferon (or receptor tyrosine kinase inhibitors)
Interleukin- 2
