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RWJ Endo Repro > Male Cancer > Flashcards

Male Cancer Flashcards

1
Q

Testicular lymphatics drain to which two nodes?

A
  1. Lumbar
  2. Para-aortic
    (NOT INGUINAL)
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2
Q

The Prostate lymph goes to the ____ nodes

A

Hypogastric

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3
Q

Vast majority of early prostate cancers are ____ receptor dependent

A

Androgen

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4
Q

_____ of the prostate is the most common form of cancer in men, especially OLDER men

A

Adenocarcinoma

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5
Q

Yolk Sac Tumors are the most common testi tumor in _____

A

Infants

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6
Q

Uniquely, Testicular torsion presents as _____ pain and a loss of _____ relfex in children

A
  • Abdominal

- Cremasteric

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7
Q

The Testis lymph goes to the _____ nodes

A

Paraaortic

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8
Q

Prostate Cancer histo usually includes ____ (number) of cell layers along with ____ nuclei

A
  • Single

- Large

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9
Q

Considering that the Prostate Stromal cells utilize 5-a-Reductase to make DHT and continue Stromal Proliferation; a drug such as _____ would be great to inhibit 5-a-Reductase or ALPHA-1A BLOCKERS TO RELAX THE MUSCLES

A

Finasteride

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10
Q

Teratomas are benign for ______ and malignant for _____

A
  • Pre-puberty

- Post-Puberty

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11
Q

Buzz-Word for testicular Torsion

A

“Bell Clapper Deformity”

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12
Q

The Penis lymph goes to the _____ nodes

A

Inguinal

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13
Q

In regards to Germ Cell Tumors, Embryonal Carcinoma Tumors are more AGGRESSIVE than Seminoma and may have Serum _____(yolk) and _____ (chorio) elevation

A
  • a-AFP

- HCG

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14
Q

95% of testicular cancers are germ cell tumors which are wither _____ that resemble germ cells or _________ that are undifferentiated

A
  • Seminoma

- Non-Seminoma

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15
Q

Usually from age ____ to _____ Testicular tumor is most common

A

15-35

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16
Q

Castration leads to _____ of the prostate

A

Atrophy

17
Q

A testicular hydrocele is when fluid builds up in the ___ ___

A

tunica vaginalis

18
Q

Prostate cancers typically occur in the _____ Zone of the prostate

A

Peripheral

19
Q

Key Yolk Sac Histo Finding?

A

Schiller Duval Bodies

looks like glomeruli

20
Q

Most common testicular mass in male >50 is actually a ______

A

DLBC Lymphoma

21
Q

Since choriocarcinoma makes a lot of HcG, what other hormone receptors can be activated?

A
  • Thyroid (hyper)

- FSH/LH (Gynecomastia)

22
Q

Seminomas almost never occur in _____ and have excellent prognosis

A

Infants

23
Q

Although embryonal carcinoma might have elevated Serum AFP the most common Testi tumor in infants, _____ ____ Tumors, will 100% have elevated AFP (100’s-1000’s ng/mL).

A

Yolk Sac

24
Q

To treat testicular neoplasms NEVER do what 2 things?

A
  • Biopsy
  • Cut into scrotum
    (No trans-scrotal orchiectomy or biopsy)
25
Q

Seminomas never hit infants and can contain synctiotrophoblasts that produce _____

A

HCG

26
Q

What does prostate cancer do to the bones?

A

BUILDS with osteoblasts

27
Q

BPH typically occurs in the _____ Zone of the prostate

A

Transition

28
Q

How does Finasteride treat BPH?

A

Inhibits 5-a-Reductase

Inhibits stromal proliiferation

29
Q

Priapism

A

Erection for more than 4 hrs

30
Q

2 Kinds of Non-Seminoma Testi Tumors

A
  1. Teratoma

2. Yolk sac (embryonal carcinoma or choriocarcinoma)

31
Q

Key Choriocarcinoma Lab finding?

A

Elevated hCG >100,00 mIU/mL

32
Q

Isochromosome of the short arm of chromosome 12 is PATHOGNOMONIC for _____ tumors

A

Testicular

33
Q

In the descent of the testis the coelomic cavity evaginates into scrotal swelling and forms the pocket known as _____ ____, which should obliterate

A

Processus Vaginalis

34
Q

How to treat testicular neoplasm surgically?

A
  • Remove testis and spermatic cord form inguinal ring

Radical Inguinal Orchiectomy

35
Q

2 Hormonal treatments to prostate cancer

A
  1. Continuous GnRH analog (leuoprolide)

2. AR atnagonists (flutamine)

RWJ Endo Repro (26 decks)

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