Amorosa Hypoglyc & Insulinoma

Question 1

A normal Insulin:Glucose Ratio is 0.1, signs of an insulinoma would include a ratio greater than ______

Answer 1

0.3

Question 2

What does low levels of insulin do to muscle glucose disposal?

Answer 2

Reduces it.

Question 3

What is Functional Hypoglycemia?

Answer 3

Idiopathic causes, mostly post prandial

Question 4

5 Examples of Organic Hypoglycemia

Answer 4

1. Insulinoma
2. Islet Cell Hyperplasia
3. IgF1 GIST Tumor
4. IgF2 Sarcoma
5. Autoimmune

Question 5

What are the two types of Hypoglycemia?

Answer 5

1. Functional

2. Organic

Question 6

Why does functional Reactive Hypoglycemia present with a sudden severe symptomology?

Answer 6

First Phase Insulin may be delayed

Common for Type 2 Diabetes

Question 7

Name 3 Neuroglycopenic symptoms of Hypoglycemia

Answer 7

1. Blurred Vision
2. Seizures
3. Altered Mental Status

Question 8

MEN1 is a menin tumor suppression gene on chromosome 11, whose defect is linked to what clinical manifestation?

Answer 8

Insulinoma

Question 9

3 Examples of Functional Hypoglycemia

Answer 9

1. Reactive
2. Factitious
3. Alcoholic

Question 10

How does the functional Reactive Hypoglycemia present clinically?

Answer 10

Sudden severe hypoglycemia

Question 11

What is Whipple’s triad of hypoglycemia?

Answer 11

1. Reversible with glucose
2. Sympathetic symtpoms
3. Symptomatic at,45mg/dL OR dependant on BASELINE

Question 12

Insulinomas are linked to the Gene ______ on chromosome 11

Answer 12

MEN1

Question 13

What is Organic Hypoglycemia?

Answer 13

Organ or body-related abnormality

Question 14

What causes hypoglycemic neurogenic symptoms?

Answer 14

NE and Epi release

anxiety, sweat, tremor, HTN, nausea