M4: Serous Fluids (Part 1: Intro to Transudates and Exudates) Flashcards
What are fluids within closed cavities of the body?
pleural, pericardial, peritoneal
These are seen in the cavity (space) in between of parietal and visceral membrane
Serous fluid
Serous fluid are seen in the cavity in between what (2) membranes?
Parietal and Visceral membrane
Serous fluid within 2 membranes
lines the cavity wall (outer wall)
Parietal membrane
Serous fluid within 2 membranes
covers the organ (inner wall)
Visceral membrane
- These provide lubrication
- Reduces friction & abrasion
- Ultrafiltrates of plasma
- Affected by hydrostatic and colloid pressure
Serous fluids
These are ultrafiltrates of plasma
Serous fluids
Whenever serous fluids is extracted, what procedure must be done?
blood collection
Serous fluids
T or F
After blood collection and serous fluid are collected, comparison of plasma and serous fluid will occur
T
Serous fluids
What are the (2) factors affected by hydrostatic and colloid pressure
- Production of volume
- Reabsorption
Serous fluids
increase fluid between membranes
Effusion
Specimen Collection and Handling
3 ways of aspiration
- Thoracentesis
- Pericardiocentesis
- Paracentesis
Specimen Collection and Handling
Serous fluid in lungs
Aspiration sample
Pleural
Specimen Collection and Handling
Serous fluid in heart
Aspiration sample
Pericardial
Specimen Collection and Handling
Serous fluid in abdomen
Aspiration sample
Peritoneal
Specimen Collection and Handling
Process of aspiration of pleural fluid (lungs)
Aspiration sample
Thoracentesis
Specimen Collection and Handling
Process of aspiration of pericardial fluid (heart)
Pericardiocentesis
Specimen Collection and Handling
Process of aspiration of peritoneal fluid (abdomen)
Paracentesis
Specimen Collection and Handling
Serous fluid is collected by using what instrument
Needle aspiration
Specimen Collection and Handling
Volume of serous fluid collected?
> 100 mL
Specimen Collection and Handling
4 anticoagulants used in serous fluid
- EDTA
- Heparinized
- SPS
- Plain
Specimen Collection and Handling
- Anticoagulant used in Cell counts and Differential counts
- For hematology
- Patient is suffering from an infection
4 anticoagulants used in serous fluid
EDTA
Specimen Collection and Handling
- Anticoagulant used for Culture, Microbiology and Cytology
- Observation of characteristic of cells
4 anticoagulants used in serous fluid
Heparinized or Sodium polyanethol sulfonate (SPS)
Specimen Collection and Handling
- Anticoagulant used for chemistry
- Compared frequently with Plasma Chemical Concentrations
Plain or Heparinized
Specimens for pH are maintained in what environment
Ice anaerobically
T or F
Increased temperature results to increased pH
F (decrease pH)
T or F
Specimen are processed immediately
T
T or F
Composition of blood plasma and serous fluid are not the same
F (ALMOST THE SAME)
T or F
Serous fluid specimens should be left in room temperature
F (ICE)
form because of a systemic disorder that disrupts the balance in the regulation of fluid filtration and reabsorption
Effusions
These are effusions that form because of a systemic disorder that disrupts the balance in the regulation of fluid filtration and reabsorption
- Transudates
- Exudates
Effusion
- Changes in Hydrostatic Pressure
- Increase (Imbalance) Pressure = Affect production and reabsorption
- Underlying disease
- CHF (Congestive heart failure) or
Hypoproteinemia associated with Nephrotic syndrome
Transudates
Effusion
- Directly involve the membranes of cavity (No underlying disease)
- Infections and malignancies
Exudates
Transudate or Exudate
Appearance:
Clear, Pale Yellow
WBC Count: < 1000/uL (Pleural, Pericardial); < 500/uL (Peritoneal)
Spontaneous Clotting: No
Fluid total protein: 30g/L or Less
Fluid:Serum protein ratio: <0.5
Fluid:Serum LD ratio: <0.6
Fluid LD: <0.67 x ULN serum
Pleural fluid cholesterol: <45 - 60 mg/dL
Pleural fluid:serum Cholesterol Ratio: <0.3
Pleural fluid:Bilirubin Ratio: 0.6
Serum-ascites Albumin gradient: >1.1
Glucose: Equal to Serum
Specific gravity: <1.015
Transudate
Transudate or Exudate
Appearance:
Cloudy, Color variable
WBC Count: > 1000/uL
Spontaneous Clotting: Possible
Fluid total protein: >30g/L
Fluid:Serum protein ratio: >0.5
Fluid:Serum LD ratio: >0.6
Fluid LD: >0.67 x ULN serum
Pleural fluid cholesterol: >45 - 60 mg/dL
Pleural fluid:serum Cholesterol Ratio: >0.3
Pleural fluid:Bilirubin Ratio: >0.6
Serum-ascites Albumin gradient: <1.1
Glucose: Less than or Equal to Serum
Specific gravity: >1.015
Exudate
Transudate or Exudate
Appearance: Clear, Pale Yellow
Transudate
Transudate or Exudate
Appearance: Cloudy, Color variable
Exudate
Transudate or Exudate
NO spontaneous clotting
Transudate
Transudate or Exudate
Possible spontaneous clotting
Exudate
Transudate or Exudate
Glucose: Equal to Serum
Transudate
actually can be both kasi exudate can be less or equal to serum
Transudate or Exudate
Glucose: Less than or Equal to Serum (Microorganisms consumes the glucose)
Exudate
Transudate or Exudate
Specific gravity: <1.015
Transudate
Transudate or Exudate
Specific gravity: >1.015
Exudates
Transudate or Exudate
T or F
Exudate’s appearance is cloudy, color variable due to the presence of microorganism
T
Transudate or Exudate
T or F
Exudate’s appearance can be color green or red due to the presence of microorganism
T