Lyme Disease Flashcards
What bacteria causes Lyme disease?
spirochaete Borrelia burgdorferi
How is lyme disease spread?
ticks
Early infective features
erythema migrans
- ‘bulls-eye’ rash 1-4 weeks after initial bite
- systemic features (headache/ lethargy/ fever/ joint pain)
Late infective features (after 30 days)
- heart block
- peri/myocarditis
- facial nerve palsy
- radicular pain
- meningitis
Erythema migrans is an indication to start antibiotics. TRUE/FALSE?
TRUE
1st Line investigation for Lyme disease
enzyme-linked immunosorbent assay (ELISA) antibodies to Borrelia burgdorferi
Management of Lyme disease
Doxycycline (if early)
Amoxicillin if doxycycline is contraindicated (e.g. pregnancy)
Ceftriaxone if disseminated disease
What is Jarisch-Herxheimer reaction?
Reaction after first dose of antibiotic
- fever
- rash
- tachycardia