CMV Flashcards
1
Q
What group of viruses does CMV belong to?
A
Herpes
2
Q
What percentage of the population have been exposed to CMV?
A
50%
(only causes disease in immunocompromised)
3
Q
Typical cell appearance in CMV
A
‘Owl’s eye’
- intranuclear inclusion bodies
4
Q
Describe the clinical features of Congenital CMV
A
- growth retardation
- pinpoint petechial ‘blueberry muffin’ skin lesions
- microcephaly
- sensorineural deafness
- encephalitiis (seizures)
- hepatosplenomegaly
5
Q
Describe the clinical features of CMV mononucleosis
A
- infectious mononucelosis-like illness
- may develop in non-immunosuppressed individuals
6
Q
Who normally develops CMV retinitis
A
HIV patients with a low CD4 count (< 50)
IV ganciclovir is the treatment of choice
7
Q
Presenting complaint in CMV retinitis
A
visual impairment e.g. ‘blurred vision’.
8
Q
Fundoscopy shows:
- retinal haemorrhages and necrosis
- ‘pizza’ retina
A
CMV Retinitis
9
Q
Treatment for CMV retinitis
A
IV ganciclovir
10
Q
Other organs where CMV may manifest
A
CMV encephalopathy
(HIV pts with low CD4 counts)
CMV pneumonitis
CMV colitis
11
Q
A
