Leprosy Flashcards
1
Q
What organism is responsible for leprosy?
A
Mycobacterium leprae
2
Q
What is leprosy and where does it affect?
A
granulomatous disease
- affects peripheral nerves and skin
3
Q
Clinical features of leprosy
A
- hypopigmented skin (buttocks, face, and extensor surfaces)
- sensory loss
4
Q
Describe the difference in leprosy infection depending on cell mediated immunity
A
Low cell mediated immunity → lepromatous leprosy
- extensive skin involvement
- symmetrical nerve involvement
High cell mediated immunity →
- tuberculoid leprosy
- limited skin disease
- asymmetric nerve involvement
- hair loss
5
Q
Management of leprosy
A
rifampicin
dapsone
clofazimine
6
Q
A