Liver Physiology + Function Flashcards
75% blood supply to liver is from?
Portal vein
25% , blood supply to liver is from?
Proper hepatic artery
What brings nutrient rich blood into the liver?
Portal vein
What takes oxygenated blood into the liver?
Proper hepatic artery
What takes deoxygenated blood back to the vena cava?
Hepatic vein
Lobules are?
Collection of cells
Functional unit of the liver
Structure of hepatic lobule?
Hexagonal
Sinusoids define:
Small blood vessels between radiating rows of hepatocytes
Characteristics of sinusoids:
One cell thick
Nutrient exchange
Gaps that allow macromolecules to pass through
Hepatic lobule consists of?
Portal triad
Sinusoids
Central vein ( hepatic vein)
Hepatocyte
Kupffer cell
Portal triad
Bile duct
Portal vein
Hepatic artery
Kupffercells are?,
Type of tissue macrophage ( performs a lot of defence functions)
Canalinculi
Series of channels between cells
How does there billiary systems structure support function?
Two separate blood supplies and separation of blood from bile
Massive SA for exchange of molecules
Sinusoids structure allows exchange of large solutes
Kupffer cells form a protective barrier
Biliary system: Bile secreted by hepatocytes then…..
canalinculi —-> Collected by system of ducts (ductules)—->
Which drain into common hepatic duct (multiple bile duct)—-> to the common bile duct
Bile is secreted by?
Hepatocytes