Integrated Control Of Bp Flashcards

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1
Q

Blood pressure =

A

Cardiac output X TPR

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2
Q

Cardiac output=

A

Stroke volume x HR

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3
Q

Baro receptors located many in:

A

Aortic arch and carotid sinus

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4
Q

Characteristics of baroreceptors?

A

Unmyelinated nerve fibres
Stretch sensitive
Respond to the magnitude of pressure change and rate of change

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5
Q

Blood pressure regulation centre is?

A

Nucleus tractus solitarius NTS

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6
Q

Beginning of the vagus nerve is called?

A

Nucleus ambiguus

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7
Q

NTS has 2 nerves:

A

Activates nucleus ambiguus
Activates nerve At CVLM which inhibits nerve at RVLM

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8
Q

Rostral ventrolateral medulla RVLM define

A

Brain region that is responsible for basal and reflex control of sympathetic activity associated with cardiovascular function

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9
Q

Pressor area of the medulla known as

A

RVLM

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10
Q

Nerves in RVLM are?

A

Sympathetic that go to heart/ blood vessels

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11
Q

RVLM receives what signal from CVLM?

A

Inhibitory GABAergic input

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12
Q

CVLM function

A

Inhibits RVLM

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13
Q

Stretch receptor: increase in stretch ( increase MAP) physiology:

A

Increased BR firing:

Increase PNS ( parasympathetic vagal tone) activation → increase in ACh → decreased HR
AND
Decrease SNS (more inhibition) → decrease in NA → decreased HR and TPR

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14
Q

Stretch receptor: decrease in stretch ( increase MAP) physiology:

A

Decreased BR firing: ‘

Decrease PNS ( parasympathetic vagal tone) activation → decrease in ACh → increased HR
AND
Increase SNS ( less inhibition) →increase in NA →increased HR and TPR

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15
Q

Baroreflex function

A

Adjusts CO and peripheral vascular tone to stabilise arterial pressure

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16
Q

Arterial resistance isimportant for?

A

Control of bp

17
Q

BR in carotid sinus and aortic arch pathway:

A

Carotid sinus = nerves CN IX (glossopharyngeal)
Aortic arch = nerves CN X (vagus X)
These terminate in NTS in medulla of brain stem
Relay to other medullary regions and also ‘higher’ centres

18
Q

M3 receptors on the endothelium leads to? Overall

A

Nitric oxide (NO) gas release