Lecture 5 Block 3 Flashcards

1
Q

what are special senses

A

in specialized sensory organ

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2
Q

what are special somatic senses

A

visual and auditory systems

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3
Q

what are special visceral senses

A

gustatory and olfactory

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4
Q

what are general senses

A

all over the whole body

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5
Q

what are examples of special senses

A

vision, hearing, taste, and smell

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6
Q

what are examples of general somatic senses

A

pain, temperature, touch, pressure, and body position

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7
Q

what are the 5 types of sensory transduction based of stimulus modalities

A
  1. chemo: tastings, olfactants, irritants
  2. photo: photons
  3. mechano: sounds, acceleration, vibration, pressure
  4. thermo: hot and cold temperatures
  5. Noci: a variety of strong noxious stimuli
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8
Q

what are sensory receptors

A

cells that convert sensory signals to electrochemical signals to be transmitted to the brain

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9
Q

what are the two types of sensory receptors

A

neurons and epithelial cells

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10
Q

what do neuronal receptors do

A

send axons to CNS or other peripheral neurons

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11
Q

what do epithelial sensory receptors do

A

synapse on sensory neurons which in turn sends axons to CNS

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12
Q

describe the stimulus induced change in the membrane potential of the sensory receptor cell

A
  1. can be depolarizing or hyperpolarizing
  2. it is graded and increases as stimulus becomes stronger
  3. can trigger transmitter release in some receptor cells, and trigger AP in other receptor cells
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13
Q

what type of receptor mediates salty taste

A

ENaC

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14
Q

what type of receptor mediates sour taste

A

H+ activated TRPP3 channel

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15
Q

what do both ENaC and H+ activated TRPP3 channels do

A
  1. activate ion channels
  2. depolarize the taste receptor cell, generating receptor potential
  3. activate Ca2+ channels
  4. release transmitter and activate nerve terminal
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16
Q

what are sweet, umami, and bitter tastes mediated by

A

GPCRs

17
Q

what is the pathway of sweet, umami, and bitter food tastants

A
  1. tastings bind to GPCR which activates PLC
  2. IP3 increase
  3. Ca2+ release from ER
  4. TRPM5 activation sodium entry
  5. depolarize the taste receptor cell
  6. Ca2+ entry through voltage gated Ca2+ channel
  7. transmitter release
18
Q

what autonomic nerves do sensory nerve fibers accompany

A

parasympathetic vagal nerve and sympathetic nerves to spinal cord

19
Q

what does visceral pain result from

A

chemical irritation or inflammation