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AGBI 410 > Lecture 23 and 24 > Flashcards

Lecture 23 and 24 Flashcards

1
Q

transmembrane differences in proton concentration are the reservoir for the energy extracted from their biological oxidation rxns

A

chemiosmotic theory

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2
Q

how many membranes of the mitochondria

A

2

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3
Q

in mitochrodira, electron transport starts from what

A

NADH or FADH2

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4
Q

in mitochrodira, electron transport goes to what

A

CoQ, cytochromes, Fe-S cluster proteins

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5
Q

segregates the intermediates and enzymes of cytosolic and matrix metabolic pathway s

A

inner mitochondrial matrix

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6
Q

lipid soluble benzoquinone with a long isoprenoid side chain

A

ubiquinone

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7
Q

another name for ubiquinone

A

coenzyme Q

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8
Q

how many electrons can ubiquinone accept

A

one or two

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9
Q

proteins with characteristic strong absorption of visible light due to iron containing heme prothetic groups

A

cytochromes

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10
Q

proteins that contain iron in association with inorganic sulfur atoms and/or with the sulfur atoms of Cys residues in the proteins

A

iron sulfur proteins

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11
Q

complex 1 ETC

A

NADH dehydrogenase

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12
Q

ubiquinone turns to what in complex 1

A

ubiquinol

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13
Q

how many H+ pumped via complex 1

A

4

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14
Q

how many polypeptide chains in complex 1

A

40+

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15
Q

what is complex 2 in ETC

A

succinate dehydrogenase

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16
Q

how many H+ pumped by complex 2

A

0

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17
Q

e transfer in complex 2

A

FADH2 to Q

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18
Q

complex 3 in ETC

A

cytochrome bc complex

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19
Q

e transfer in complex 3

A

ubiquinol to Cyt C

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20
Q

how many H+ pumped via complex 3

A

4

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21
Q

q cycle completes e- transfer from what to what

A

QH2 to cyt c

22
Q

how many times does q cycle have to run to complete e transfer

A

2

23
Q

how many e- does cyt c carry

A

1

24
Q

how many cyt c molecules made from 1 QH2

A

2

25
Q

what is complex 4 in ETC

A

cytochrome oxidase

26
Q

e transfer of complex 4

A

cyt c to o2

27
Q

o2 reduced to what in complex 4

A

h2o

28
Q

how many H+ pumped for complex 4

A

4 for each O2 reduced to h2o

29
Q

describes coupling of ATP synthase to an electrochemical proton gradient

A

chemiosmotic model

30
Q

2 subunits of ATP synthase

A

F1 and F0

31
Q

1 full rotation of ATP synthase yields what

A

3 ATp

32
Q

what is required from 1 fill rotation of ATP synthase

A

9 protons

33
Q

anti porter that moves ADP into the matrix and ATP out of

A

adenine nucleotide transferase

34
Q

promotes symport of 1 H2PO4- and one H+ into the matrix

A

phosphate translocase

35
Q

a complex of ATP synthase and both translocases

A

ATP synthesome

36
Q

catalyzes conversion of superoxide and 2 proton to H2o2 and o2

A

superoxide dismutase

37
Q

converts h2o2 to h2o

A

glutathione peroxidase

38
Q

signals reflecting insufficient O2

A

low ROS levels

39
Q

number of moles of Pi consumed in. phosphorylation to the number of moles of oxygen atoms consumed in oxidation

A

P/O ratio

40
Q

p/o when NADH is oxidized

A

2.5

41
Q

p/o when FADH is oxidized

A
  1. 5
42
Q

one NADH pumps how many protons

A

10 H+

43
Q

1 FADH2 pumps how many protons

A

6+

44
Q

how many h+ makes 1 ATP

A

4

45
Q

inner mitochondrial matrix is impermeable to what

A

NADH and NAD

46
Q

malate aspartate shuttle moves what

A

NADH equivalents

47
Q

NADH equivalents moved by the malate aspartate shuttle enter where and yield what

A

complex 1 and p/o of 2.5

48
Q

where do NADH equivalents enter via glycerol 3 phosphate shuttle and yield what

A

complex 3, yield p/o 1.5

49
Q

what kind of tissue is associated with increase in heat

A

brown adipose tissue

50
Q

weak acids that carry protons across inner mitochondrial membrane

A

DNP and FCCP

51
Q

in an uncoupling protein , what inhibits ATP syn

A

antibiotics

52
Q

e transfer in complex 1 etc

A

NADH to Q

AGBI 410 (26 decks)

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