Finishing up Flashcards
what pathway is from scratch
denovo
important part of pyrimidine and purine synthesis
PRPP
enzyme of first step of purine synthesis
glutamine PRPP amidotransferase
only enzyme to use NADP+ and NAD+
glutamate dehydrogenase
how is amp / gmp synthesis regulated
by feedback inhibiton
glutamine synthetase turns what to what
glutamate to glutamine
increase in glutamine does what (glutamine synthetase)
inhibits Uridylation, glutamine synthetase is deactivated
increase in alpha keto glutarate does what (glutamine synthetase)
increases uridylation, causes glutamine synthetase to be deadenylated
active form of glutamine synthetase
deadenylated
deactive form of glutamine synthetase
adenylate
increase in ATP does what (glutamine synthetase)
increases uridylation, causes deadenylation of glutamine synthetase
albinism defective enzyme
tyrosine 3 monooxygenase (tyrosinase)
carbamoyl phosphate synthase 1 deficiency defective enzyme
named
MSUD defective enzyme
branched chain alpha keto acid dehydrogenase complex
phenylketonuria defective enzyme
phenylalanine hydroxylase