Finishing up Flashcards

1
Q

what pathway is from scratch

A

denovo

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2
Q

important part of pyrimidine and purine synthesis

A

PRPP

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3
Q

enzyme of first step of purine synthesis

A

glutamine PRPP amidotransferase

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4
Q

only enzyme to use NADP+ and NAD+

A

glutamate dehydrogenase

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5
Q

how is amp / gmp synthesis regulated

A

by feedback inhibiton

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6
Q

glutamine synthetase turns what to what

A

glutamate to glutamine

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7
Q

increase in glutamine does what (glutamine synthetase)

A

inhibits Uridylation, glutamine synthetase is deactivated

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8
Q

increase in alpha keto glutarate does what (glutamine synthetase)

A

increases uridylation, causes glutamine synthetase to be deadenylated

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9
Q

active form of glutamine synthetase

A

deadenylated

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10
Q

deactive form of glutamine synthetase

A

adenylate

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11
Q

increase in ATP does what (glutamine synthetase)

A

increases uridylation, causes deadenylation of glutamine synthetase

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12
Q

albinism defective enzyme

A

tyrosine 3 monooxygenase (tyrosinase)

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13
Q

carbamoyl phosphate synthase 1 deficiency defective enzyme

A

named

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14
Q

MSUD defective enzyme

A

branched chain alpha keto acid dehydrogenase complex

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15
Q

phenylketonuria defective enzyme

A

phenylalanine hydroxylase

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16
Q

2 amino group donors

A

glutamine, glutamate

17
Q

2 starting materials for carbamoyl phosphate

A

bicarbonate, ATP

18
Q

what happens to bicarbonate in carbamoyl phosphate

A

phosphorylated by ATP

19
Q

glutaminase does what

A

glutamine to glutamate

20
Q

glutamine dehydrogenase does what

A

glutamate to alpha ketoglutarate