Day 10

Question 1

enzymes are complimentary to what

Answer 1

transition state

Question 2

rate eon for a one substrate enzyme catalyzed reaction

Answer 2

micaelis menten eqn

Question 3

what is Michaelis menten eqn

Answer 3

initial velocity = (vmax x [S])/km + [S]

Question 4

for reactions with two steps, km equals what

Answer 4

km= (k2+k-1)/k1

Question 5

what represents slope in line weaver burk

Answer 5

Km/vmax

Question 6

what represents y int in line weaver burk

Answer 6

1/vmax

Question 7

enzyme inhibition has two broad categories, what are they

Answer 7

reversible and irreversible

Question 8

competes with the substrate for the active site of an enzyme

Answer 8

competitive inhibotr

Question 9

increases km, vmax uneffected

Answer 9

competitive inhibotor

Question 10

WHAT is value of alpha prime for competitive inhibitor

Answer 10

1

Question 11

slope changes, y int stays the same

Answer 11

competitive inhibition

Question 12

binds at a site distinct from the substrate active site

Answer 12

uncompetitive inhibitor

Question 13

binds only to the ES complex

Answer 13

uncompetitive inhibitor

Question 14

causes decrease in both km and vmax

Answer 14

uncompetitive inhibiton

Question 15

alpha value for uncompetitive inhibiton

Answer 15

1

Question 16

y int changes, slope stays the same

Answer 16

uncompetitive inhibition

Question 17

binds at site distinct from the substrate active site

Answer 17

mixed inhibitor

Question 18

binds to either E or the ES complex

Answer 18

mixed inhibitor

Question 19

what does mixed inhibitor do to km and vmax

Answer 19

increases km, decreases vamx

Question 20

bind covalently with or destroy a functional group on an enzyme that is essential for the enzymes activity or form a highly stable non covalent association

Answer 20

irreversible inhibitor

Question 21

types of regulation of enzymes

Answer 21

positive or negative

Question 22

activators cause the curve to become what

Answer 22

more hyperbolic, more to the left

Question 23

inhibitor may cause the curve to become what

Answer 23

more sigmoidal, moving to right

Question 24

inactive precursor that is cleaved to form an active protease enzyme

Answer 24

zymogen

Question 25

precursors that are cleaved to form other proteins

Answer 25

pro protein or proenzyme