Lecture 21: Fluke diseases Flashcards
All trematodes are hermaphrodites except ___
Blood flukes (ex: H. Americana)
Describe the basic life cycle of trematodes
- Eggs are released in DH feces
- Hatch into Miracidia
- Miracidia enter IH (snail)
- Miracidia undergo asexual reproduction in IH and turn into cercariae (infective stage)
- Cercariae are ingested by definitive host or penetrate skin
- Metaccercariae (or cercariae) develop into adult worms in DH
What is the infective stage called in trematodes
Metacercariae
What is the scientific name for common liver fluke
Fasciola hepatic
What disease does F. Hepatica cause
Fascioliasis
Where do adult F. Hepatica worms colonize
Bile ducts
What is the intermediate host for F. Hepatica
Lymnaeid snails
Describe the life cycle of F. Hepatica
- Eggs exit feces of DH
- Miracidia ingested by lymnaeid snails (IH)
- Cercariae develop and are present on vegetation
- Ingested by DH
- Enter duodenum
- Travel to liver
- Adult worms end up in bile ducts
What is acute fascioliasis
Infection of young flukes that parasitize the liver of DH—> cause hemorrhage and inflammation
What are the definitive hosts of F. Hepatica
Herbivores- cattle, sheep, camelids
What definitive host for F. Hepatica is most likely to suffer severe disease
Sheep, can be fatal within 2-6 weeks
Sheep liver that shoes hemorrhage and inflammation, what trematode most likely caused this
F. Hepatica
what trematode is this? Commonly causes liver damage in sheep and cattle. Intermediate host is lymnaeid snails
F. Hepatica
What is chronic fascioliasis
Moderate infection over time that is characterized by presence of adult flukes in bile duct
What clinical symptom is typical of chronic fascioliasis
Bottle jaw
What fecal dx method is used for F. Hepatica
Fecal sedimentation
What drugs tx F. Hepatica
Clorsulon, ivermectin, albendazole
What trematode is this? Commonly infects sheep and cattle. Results in bottle jaw
F. Hepatica egg
What species does Paragonimus kellicotti infect and where is the infection
Lungs of cats and dogs
How do cats and dogs become infected with P. Kellicotti
Eating infected crayfish or eating animals that ate the crayfish
What is the preferred 1st intermediate host of P. Kellicotti
Slender walker snails
What is the preferred 2nd intermediate host for P. Kellicotti
Crayfish
What does P. Kellicotti cause/clinical signs
Pleuritis, pleural effusion, pneumothorax, pneumonia, cough, dyspnea
The following X-ray and fecal sample were observed in a dog that recently ate a crayfish. Dog is experiencing respiratory issues. what parasite is the dog infected with
P. Kellicotti
How do you diagnose P. Kellicotti
- Fecal sedimentation
- Tracheal wash
- Pleural biopsy
- Chest rads
What is the tx for P. Kellicotti
Praziquantel and fenbendazole
What trematode egg is this? Dog/cat presented with respiratory signs
P. Kellicotti
Where do adult worms of Dicrocoelium dendritium live in DH
Pancreatic duct, bile duct, and gallbladder
What are the DH of dicrocoelium dendritium
Domestic ruminants
How do animals become infected with D. Dendritium
Eating ants encysted with metacercariae
What is the preferred 1st intermediate host of D. Dendriticum
- Terrestrial snails
What is the preferred 2nd intermediate host of D. Dendriticum
Ants
Sheep presents with hepatic cirrhosis, decreased wool production, decreased lactation. (Also likes to eat ants) what parasite is the sheep infected with
D. Dendriticum
How can you dx D. Dendriticum
Fecal float
What is the treatment for D. Dendriticum (cattle and small ruminants vs llamas and alpacas)
Cattle and SR: albendazole and netobimin
Llamas and alpacas: praziquantel
What fluke family is known to penetrate skin of DH
Schistosomatidae
At what life stage do schistosomatidae flukes penetrate the skin
Cercariae (no metacercarial stage)
How does Heterobilharzia Americana infect host
Penetrate the skin
Where do the adults of H. Americana live
Mesenteric veins
What is the main reservoir and other reservoirs for H. Americana
Main reservoir: raccoons
Other: dogs, cats
What species shows the most clinical signs with infection of H. Americana
Dogs—> canine schistosomiasis
What is the intermediate host for H. Americana
Lymnaeid snails
How do dogs become infected with H. Americana
Infected lakes/streams
Dog presented with lethargy, vomiting, diarrhea, weight loss, hyporexia, anorexia, hypercalemia, PU/PD. Owner lives near a stream. The following image what obtained. What parasite is this
H. Americana
How do you dx H. Americana
- Fecal sedimentation or biopsy samples
- Abdominal rads- thickening of intestinal walls
What is the tx for H. Americana
Praziquantel and fenbendazole
what parasite causes canine schistosomiasis
H. Americana