Lecture 19: Clinical Case of cryptosporidosis

Question 1

what is cryptosporidium

Answer 1

Protozoal pathogens of humans, cattle and many other mammals and non-mammals

Question 2

What is the most significant species of cryptosporidium in cattle

Answer 2

C, Parvum

Question 3

What is the #2 cause of diarrhea in the cows

Answer 3

Cryptosporidosis

Question 4

Diarrhea is responsible for ___calf mortality `

Answer 4

Half

Question 5

How does the infection with cryptosporidium begin

Answer 5

Attachment to intestinal epithelium

Requires expression of key virulence proteins

Question 6

Cryptosporidium causes loss of __resulting in malabsorption and maldigestion resulting in ___

Answer 6

Villus absorptive epithelial cells, resulting in diarrhea

Question 7

What are the treatment options for cryptosporidium

Answer 7

Nitazoxanide (no very effective)

No vaccines, so leaves supportive care

Question 8

What is indicated here and what is most likely cause

Answer 8

Cryptosporidium, atrophy of villus, epithelial disruption and adherent basophilic organisms to villus tip