Lecture 12 Flashcards
What does feline panleukopaenia/feline enteritis target
Rapidly dividing cells e.g. crypt cells in intestine
What are the clinical signs of feline panleukopaenia/feline enteritis
Diarrhoea, vomiting, dehydration, depression
What is the pathology of feline panleukopaenia/feline enteritis
Immunosupression and panleukopaenia Flaccid dilated red intestine with serositis Loss of villous architecture Intranuclear inclusions in enterocytes Desgumated cells in crypts Congenital cerebellar hypoplasia
What does canine parvovirus target
Rapidly dividing cells e.g. crypt cells in intestine
Why do young pups get canine parvovirus
They aren’t protected by maternal ab
What does the outcome of feline infectious peritonitis depend on
Immune response
What are the two forms of feline infectious peritonitis
Wet form - develop wide spread vaculitis : effusion of protein-rich fluid, fibrinous polyserositis Dry form - Vaculitis but not effusion of fluid
What do both forms of FIP cause
Depression, inappetence wt loss, most die Pyogranulomatous lesions around blood vessels
What is seen with the wet form of feline infectious peritonitis
Rapid onset Thick, stringy high protein fluid in body cavity
What is seen with the dry form of feline infectious peritonitis
Insidious onset No effusion of fluid
What does histolytic ulcerative colitis affect
Young boxer dogs
What does histolytic ulcerative colitis cause
Ulcerated colon - enterocyte necrosis overlying granulomatous reaction Many macrophages in lamina propria and submucosa Lymphadenopathy
What is an immunologic intestinal disease
Inflammatory bowel disease (IBD) Diffuse eosinophilic gastroenteritis Wheat-sensitive enteropathy of Irish setters - similar to gluten intolerance in humans
What does immunologic intestinal disease cause
Malabsorption and protein losing enteropathy
What are parasitic diseases
Toxocara (round worms) Hookworms Cestodes Coccidiosis
How to toxocara spread
Intrauterine transmission last 10 days of pregnancy Through milk Ingestion of eggs from environment
What do hookworms do
They are blood feeders in the mucosa
How can dogs get infected with hookworm
Transplacental/colostral infection Larvae ingested or skin penetration
What do cestodes require
Intermediate hosts Worms compete with host for nutrients
What does coccidiosis cause
Diarrhoea in pups and kittens
What sort of pathogen is coccidiosis
Obligate intracellular pathogen
What does tritrichomonas foetus cause in cattle
Reproductive loss
What can be seen histologically with tritrichomonas foetus
Chronic colitis
How is tritrichomonas foetus diagnosed
Faecal wet mounts Pyriform or crescent shaped organisms
