Lecture 10 RNA Processing Flashcards
1
Q
Where do all RNA’s come from?
A
Transcription
2
Q
What is cleavage?
A
Cutting primary transcript (identical to DNA seq.) into pieces
3
Q
What is base modification
A
When the base is chemically changed (uracil)
4
Q
What is RNA editing
A
Changes one nucleotide into another
5
Q
What is 5’ Cap?
A
A cap that is added to the 5’ tail to protect mRNA degration
6
Q
What is 3’ Cap?
A
A cap that is added to the 3’ tail to protect mRNA degration
7
Q
What is splicing?
A
removing introns and keeping exons
8
Q
What is a spliceosome
A
A complex of snRPs (RNA and protein)
9
Q
What are snRPs
A
Small nuclear ribo proteins
10
Q
What are snRNAs
A
small nuclear RNA’s (part of snRP’s)
11
Q
What is alternative splicing
A
combining exons to make different mRNA’s and proteins
12
Q
Isoforms
A
different proteins that result from alternative proteins
