Lec 13- Autonomic and somatic nervous system Flashcards

1
Q

Preganglionic neuron

A

originates in the brainstem or the spinal cord.

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2
Q

Postganglionic neuron

A

lies outside the central nervous system in collections of nerve cells called autonomic ganglia.

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3
Q

Autonomic ganglion

A

are clusters of neuronal cell bodies and their dendrites. They are essentially a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery.

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4
Q

Sympathetic nervous system

A

fight or flight

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5
Q

Sympathetic chain ganglia/paravertebral ganglia

A

Most then synapse on postganlionics here.

Which form chain of interconnected ganglia paralleling spinal cord.

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6
Q

Adrenal medulla

A

is a modified sympathetic ganglion that does not give rise to postganglionic fibers.
Release 85% Epi and 15% Norepi in response to preganglionic stimulation.

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7
Q

Epinephrine (Epi)

A

adrenaline.

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8
Q

Parasympathetic nervous system (PNS)

A

rest and digest.

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9
Q

Terminal ganglia

A

located next to or within target organ.

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10
Q

Vagus nerve/cranial nerve X

A

carries most parasymp fibers.

Innervates heart, lungs, esophagus, stomach, pancreas, liver, small intetsine, and upper half of large intestine.

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11
Q

Cholinergic -> ACh

A

Parasymp postganglionics, because release acetylcholine.

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12
Q

Adrenergic -> NE

A

Most symp postganlionics release Norepi

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13
Q

ACh/acetylcholine

A

Symp and parasymp preganglionic fibers both release this.

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14
Q

NE/Noreoinenephrine

A

Most symp postganlionic fibers release this.

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15
Q

Agonist

A

Binds to the NT’s receptor and causes the same response as the NT would.

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16
Q

Antagonist

A

Binds with the receptor, preventing the NT from binding and causing a response, yet causes no response itself.

17
Q

Nicotine

A

An agonist to nicotinic

18
Q

Curare

A

An antagoist to nicotinic

19
Q

Muscarine

A

An agonist to muscarinic

20
Q

Atropine

A

An agonist to muscarinic

21
Q

a1,a2,B1,B2

A

two major classes of adrenergic receptors for NE and Epi

22
Q

Phenylephrine (PE)

A

Alpha receptor non-selective agonist.

23
Q

Phenocybenzamine

A

Alpha receptor non-selective antagonist.

24
Q

Isoproteronol

A

Beta receptor non-selective agonist.

Treats congestive heart failure.

25
Q

Albuterol

A

B2 agonist.

Used in inhalers for bronchial dialation.

26
Q

Propranolol

A

Beta receptor non-selective antagonist.

Decreases stimulation of heart rate via B1, but bronchial constricts asthmatics via antagonism of B2.

27
Q

Atenolol

A

Current beta-blocker (antagonist) for angina pectoralis, which is selective for B1 receptors.

28
Q

Ephedrine

A

general stimulant of NE release.

29
Q

Amphetamines

A

general stimulant of NE release.

30
Q

Cocaine

A

Prevent NE re-uptake.

31
Q

Variscosites

A

NT released along a series of synapses.

swellings in autonomic postganglionic fibers that simultaneously release NT over a large area of an innervated organ.

32
Q

Synapses en passant

A

Variscosities.

Multiunit requires nerve stimulation by ANS

33
Q

Dual innervation

A

Innervation of a single organ by both branches of the ANS.