Lec 10- Skeletal Muscle Mechanics and Metabolism Flashcards

1
Q

Atrophy

A

Muscle fibers become smaller; actin and myosin content decreases.

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2
Q

Hypertrophy

A

Muscle growth

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3
Q

Hyperplasia

A

An increase in the number of muscle cells.

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4
Q

Series elastic components

A

Tendons and connective tissue are elastic and absorb tension as muscle contracts.

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5
Q

Recruitment

A

More and more motor units are recruited, or stimulated to contract simultaneously.

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6
Q

Summation

A

AP add together to produce greater tension in the fiber than that produced by a single ap.

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7
Q

Tetanus

A

Rapid stimulation that does’t allow any time to relax. Maximal sustained contraction.

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8
Q

Twitch

A

Not considered to be normal, rare occurrence.

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9
Q

Isometric contraction

A

Exerted force does not cause load to move and length of fibers remains constant. More force/tension is generated.

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10
Q

Isotonic contraction

A

force remains constant as muscle changes length.

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11
Q

Motor unit

A

control a various number of muscle fibers.

The smaller amount of muscle fibers innervated = fine control.

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12
Q

Length-tension relationship

A

Length at which optimal force can be achieved during a tetanic contraction.

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13
Q

VO2 max

A

or maximal oxygen consumption, refers to the maximum amount of oxygen that an individual can utilize during intense or maximal exercise.
50-70% in healthy people

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14
Q

Lactate threshold

A

is % of max O2 uptake at which there is a significant rise in blood lactate levels

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15
Q

Oxygen debt

A

AKA EPOC
Takes while for O2 to go back to normal because it was lost due to exercise and is needed for metabolism of lactate acid (which was built up from anaerobic respiration)

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16
Q

Phosphocreatine/Creatine

A

source of high energy Ps to regenerate ATP from ADP.

17
Q

Slow twicth/Type 1/Slow Oxidative

A

Slow speed of contraction, high resistance to fatigue, low myosin-atpase activity

18
Q

Fast twitch/Type 2A/Fast Oxidative

A

Fast speed of contraction, intermediate resistance to fatigue, high myosin-atpase activity

19
Q

Fast twitch/Type 2X/Fast glycolytic

A

Fast speed of contraction, low resistance to fatigue, high myosin-atpase activity

20
Q

Myoglobin

A

can store small amounts of O2. Red color

21
Q

Fatigue

A

Inability to maintain muscle tension at a given level despite sustained stimulation

22
Q

CPK - creatine phosphokinase

A
converts creatine to phosphocreatine.
an enzyme (a protein that helps to elicit chemical changes in your body) found in your heart, brain, and skeletal muscles.
23
Q

Curare

A

reversibly binds to the ACh receptor-channels on the motor end plate.

24
Q

Botox

A

Blocks the release of ACh from the terminal button in response to a motor-neuron AP