Lab 43: Blood Typing Flashcards
What does blood typing involve?
Blood typing involves identifying protein substances called antigens present on the outer surface of red blood cell membranes.
What antigens are of clinical importance?
The antigens of the ABO group and those of the Rh group.
How does one determine what antigens are present?
To determine what antigens are present a blood sample is mixed with blood typing sera that contain known types of antibodies.
What is the final check on blood compatibility?
a cross-matching test which small samples of the blood from the donor and the recipient are mixed to be sure agglunation does not create a transfusion reaction.
What is hemolysis?
Red blood cell destruction.
What are autologus transfusions?
Autologus transfusions are sometimes used when a surgery is elective, allowing some of the persons predonated blood to be used durign the surgery
What is the Rh factor?
An antigen commonly found on the human RBC membrane was first identified in Rhesus monkeys and it became known as the Rh factor.
What percent of american’s possess the D antigen?
85
What makes someone rh positive?
People who possess the D-Antigen on the cell membrane are considered rh positive.
What makes someone Rh negative?
People who lack the D-Antigen are considered Rh negative.
What would happen if an Rh negative mother carrying an Rh positive fetus had blood mix?
The Rh negative mother would start begin producing anti D antibodies creating complications for future pregnancies.
What is hemolytic disease of the fetus and newborn?
Also called erythroblastosis fetalis, is where the mother produces anti D antibodies while pregnant
How can Erythroblastosis be prevented?
By adminstering RhoGam.
What does Rho Gam do?
Prevents the mother from producing Anti D antibodies.
What are the RBC Antigens in A blood?
A
What are the RBC antigens in B blood?
B
What are the RBC antigens in AB blood?
A and B
What are the RBC antigens in O blood?
Neither A nor B
What are the plasma antibodies in type A blood?
Anti-B
What are the plasma antibodies in type B blood?
Anti-A
What are the plasma antibodies in type AB blood?
Neither anti-A nor Anti-B