L21: Respiratory Failure Flashcards

1
Q

What is respiratory failure

A

The inability of the lung to meet the metabolic demands of the body. Failure of tissue oxygenation or carbon dioxide homeostasis

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2
Q

Clinically how is respiratory failure defined

A

Pao2 less than 8kpa
Or
Pac02 greater than 6.5kpa

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3
Q

What are the 3 elements that cause respiratory failure

A

Alveolar hyperventilation (mechanical)
Circulation failure
Alveolar tissue problem

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4
Q

What can a mechanical failure be due to

A

Central problem
Peripheral problem
Lung structure problem

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5
Q

What are the types of respiratory failure

A

Type 1

Type 2

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6
Q

What is type 1 respiratory failure

A

Pa02 less than 8kpa with normal/low paco2 this leads to normal/high ph

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7
Q

What is the problem in type 1 respiratory failure

A

Oxygen exchange occurring at the alveolar and pulmonary circulation

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8
Q

Is there a problem with mechanical ventilation in type 1 respiratory failure

A

No

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9
Q

What does a type 1 respiratory failure lead to

A

V/Q mismatch and shunt

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10
Q

What is type 2 respiratory failure

A

Hypoxic and Paco2 greater than 6.5kpa

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11
Q

What are the underlying causes of respiratory failure

A
Sepsis
Pneumonia 
Pulmonary embolus 
COPD exacerbation 
Cardiogenic pulmonary edema
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12
Q

What are the symptoms of sepsis

A

Fever

Chills

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13
Q

What are the symptoms of pneumonia

A

Cough
Sputum production
Chest pain

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14
Q

What are the symptoms of pulmonary embolus

A

Sudden onset of shortness of breath

Chest pain

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15
Q

What are the symptoms of COPD exacerbation

A

Heave smoking
Cough
Sputum

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16
Q

What does hypotension (low blood pressure) suggest

A

Sepsis

Pulmonary embolus

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17
Q

What does hypertension (high blood pressure) suggest

A

Poor effusion : cardiogenic pulmonary edema

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18
Q

What does wheezing suggest

A

Airway obstruction

19
Q

How do we diagnose for respiratory failure

A
Arterial blood gas
Blood
Cardiac markers
Microbiology 
Chest x-ray
ECG
Echocardiogram
Pulmonary function test 
CTPA
Ct scan
20
Q

What causes a patient with respiratory failure to die

A

Hypoxia

21
Q

What is the primary objective to reverse respiratory failure

A

Reverse and prevent hypoxia

22
Q

After correcting the hypoxia in respiratory failure what is secondary objective to treat

A

Control paco2 and respiratory acidosis

23
Q

If a patient has rising paco2 what is required

A

Support to blow out co2

24
Q

How do we treat hypoxia

A

secure airway
Give supplemental oxygen
Treat underlying condition

25
Q

Why is oxygen therapy used

A

Prevent tissue hypoxia and maintain normal oxygen

26
Q

What is the most basic equipment to provide oxygen

A

Nasal cannula

27
Q

What is nasal cannula

A

Tubes with two small prongs inserted into the nose

28
Q

After nasal cannula what is used to supply oxygen

A

Simple face mask

29
Q

What is the disadvantages of simple face masks

A

Rebreathing carbon dioxide

30
Q

What is a non rebreather mask

A

A face mask attached to a bag

31
Q

What does the bag in a non rebreather mask allow

A

Act as a reservoir for oxygen and allow more oxygen to be inspired at each breath

32
Q

What are Venturi masks

A

Different sized adapters deliver different oxygen

33
Q

When simple measures of proving oxygen failure what do we need to provide a patient

A

Mechanical ventilation

34
Q

What does mechanical ventilation provide

A

The effort to breath

35
Q

What are the 2 ways mechanical ventilation be carried out

A

Non invasive with a mask

Invasive with endobronchial tube attached to a machine

36
Q

What is mechanical ventilation good to treat

A

Hypoxia

Hypercapnia

37
Q

What is hypercapnia

A

High carbon dioxide

38
Q

What does mechanical ventilation allow to rest

A

Respiratory muscles

39
Q

When is mechanical ventilation used

A
Cardiac arrest
Tachypnoae 
Acute respiratory acidosis 
Cardiogenic shock
Brain injury
40
Q

What pressure does mechanical ventilation provide

A

Positive pressure

41
Q

Does invasive mechanical ventilation completely take over breathing

A

Yes

42
Q

Why do we not want patients to reach negative pressure

A

The alveoli will collapse all the way down

43
Q

Why is positive end expiratory pressure (PEEP) used in ventilation

A

Keeps the alveolus open and prevent them from collapsing
Improve gas exchange
Treat hypoxia
Treat pulmonary edema