June 23, 2019 Flashcards
What is the definition of psychoactive drugs
- they are drugs that can alter our consciousness and perceptions
- > increase our mood, calm us down, make us feel more alert, etc
What are the three main categories of psychoactive drugs
1) Depressants
2) Stimulants
3) Hallucinogens
How do depressants affect your body’s basic functions? Focus on the body’s basic functions.
- they work to lover neural activity
- > specifically, lower the CNS activity
- > eg; decrease heart rate, decrease blood pressure, decreae reaction time/processing
-note that depressants vasodilate in low concentration but vasoconstrict at high concentrations
What are the three categories of depressants
1) Alcohol
2) Barbituates
3) Benzoddiazepenes
Describe the general characteristics of barbiturates
- they depress CNS activity
- > act as anesthesia or anticonvulsant
- not often prescribed due to negative side effects
- > eg; reduced memory, judgement and concentration
Describe the general characteristics of benzodiazepines
- same thing as barbiturates
- >aims to aid sleep or help with anxiety(anticonvulsant)
Through what mechanism does benzodiazepines work
- they enhance your brain’s response to GABA
- > they open up GABA activated chloride channels in your neurons
- > making the neurons more negatively charged
How do stimulants affect the body
- they work to excite your CNS
- > increase the heart rate and blood pressure
- > more awake, more alert
- note that nicotine, THC are also stimulant
- > THC can also be classified as a hallucinogen and or a depressant
-they are vasoconstrictors
What is the mechanism of cocaine
-it blocks dopamine reuptake
What is the mechanism of amphetamines
- block dopamine reuptake
- >stimulate presynaptic dopamine release as well
What is the mechanism of caffeine
-it works to inhibit the enzyme that breaks down cAMP
What is the mechanism of nicotine
- it acts on acetylcholine
- >it is an acetylcholine receptor agonist
What neurotransmitter does LSD modify
-it modifies the serotonin neurotransmitter
How are opioids similar to depressants
- they decrease CNS function, decrease heart rate and blood pressure
- > also cause relaxation and induce sleep
How do opiates relate to blood vessel activity and that of the pupils
-they constrict the pupils and are vasodilators