Inotropic Drugs Flashcards
Inotropic drugs
drugs that increase the force of myocardial contraction
digoxin is a?
cardiac glycoside
Inotropic drugs affect?
the force of muscular contraction
positive inotropic drugs?
increase the force of contraction (digoxin)
negative inotropic drugs?
decrease the force of contraction (beta blockers)
chronotropic drugs effect?
the rate of the heartbeat
positive chronotropic drugs
increase the heart rate
Negative chronotropic drugs
decrease heart rate (digoxin)
Dromotropic drugs affect?
the conduction speed of electrical impulses
negative dromotropic drugs?
slow down the conduction speed (digoxin)
3 S’s of digoxin?
- Strengthens contraction
- Slows hear rate at SA node
- Slows conduction speed at AV node
digoxin can promote
diuresis due to increased kidney perfusion
digoxin has a?
narrow therapeutic index (window)
What can increase digoxin toxicity?
low potassium levels
what are the earlier signs of digoxin toxicity?
anorexia, nausea, vomiting and diarrhea