Drugs for PD

Question 1

what are the two main drugs used for PD?

Answer 1

Levodopa-carbidopa and benztropine

Question 2

why can’t pure dopamine be used to treat PD?

Answer 2

it cannot cross the BBB

Question 3

when does levodopa fail to treat PD?

Answer 3

about 5-10 years after beginning therapy

Question 4

Carbidopa is given with levodopa to?

Answer 4

prevent levodopa breakdown in the periphery

Question 5

what is an ironic adverse effect of levodopa?

Answer 5

involuntary muscle movements

Question 6

what is an example of a MAOI?

Answer 6

selegiline

Question 7

When starting dopaminergic agents, assist client with walking because of _______

Answer 7

dizziness

Question 8

anticholinergics do not relieve?

Answer 8

bradykinesia

Question 9

what is an example of an anticholinergic for PD?

Answer 9

benztropine

Question 10

Levodopa is aimed at increasing dopamine release from?

Answer 10

surviving dopamine neurons

Question 11

Entacapone

Answer 11

used with levodopa to inhibit COMT (an enzyme that metabolizes levodopa) and allows more levodopa to enter brain

Question 12

Amantidine

Answer 12

causes the release of dopamine and blocks reuptake of dopamine

Question 13

People taking levodopa should avoid which type of diets?

Answer 13

high protein

Question 14

Anticholinergics are used in PD mainly to treat…?

Answer 14

muscle tremors

Question 15

Benztropine is also used to treat?

Answer 15

EPS