Antidysrythmics Flashcards
where is the origin of supra ventricular tachycardias?
the atria
what is the most common type of supra ventricular tachycardia?
atrial fibrillation
Why is AV block desirable with supra ventricular dysrhythmias?
because less of the underside activity would get transmitted to ventricles
ventricular/atrial cardiac muscle cells depend on?
sodium and potassium
action potential of ventricular/atrial muscle cells start with ______ and end with _______
start with sodium influx and end with potassium efflux
Class 1 antidysrhythmic drugs
sodium channel blockers
Class 2 antidysrythmics
beta blockers
Class 3 antidysrhythmics
potassium channel blockers and others
Class 4 antidysrthymics
calcium channel blockers
class 5 antidysrhythmics
adenosine and digoxin
All class 1 antidysrhythmics block?
sodium channels and slow depolarization
Class 1A prototype?
quinidine
quinidine is used for?
acute onset atrial fibrillation
quinidine slows atrial and ventricular rates but?
does not affect rhythm
wolff-parkinson-white syndrome is associated with?
quinidine
Class 1 B prototype?
lidocaine
lidocaine is used for ______ only
ventricular dysrhythmias
class II prototype?
metoprolol
how does metoprolol work?
reduces or blocks SNS stimulation and creates AV block
Class III prototype?
amiodarone
how does amiodarone work?
it blocks potassium channels therefore prolonging depolarization and cardiac action potential
downside of amioderone?
can have very serious adverse effects if used for longer than 6 months.
amioderone is commonly used in those who are?
resistant to other drugs
Prototype for class IV?
diltiazem and verapamil