Antihypertensives Flashcards
What is the prototype for ACE inhibitors?
Captopril
What is the drug of choice for hypertensive clients with heart failure or diabetics?
ACE inhibitors (captopril)
ACE inhibitors prevent the breakdown of?
Bradykinin, a good vasodilator
What is a common adverse effect of ACE inhibitors?
Dry, non productive cough due to bradykinin
What is the prototype for ARBs?
Losartan
Are ARBs usually combine with ACEIs?
No
Do ARBs produce a dry non productive cough?
No
What are the prototypes for CCBs?
Diltiazem, verapamil and amlodipine
Amlodipine is different than other CCBs because?
It is vascular selective
What is a major adverse effect of verapamil/diltiazem?
Constipation
What is a common adverse effect with all CCBs?
Flushing
Which CCB does constipation occur less in?
Amlodipine
What is the prototype for BBs used for hypertension?
Metoprolol
What is the prototype for centrally acting alpha 2 adrenergic receptor agonists?
Methyldopa
What is the only hypertensive agent used in pregnancy?
Methyldopa