Infectious diseases, schizophrenia, and affective disorders

Question 1

What is the body’s natural response to injury or infection

Answer 1

inflammation

Question 2

In the CNS, the inflammatory response involves what

Answer 2

the activation of microglia which leads to neuroinflammation

Question 3

Encephalitis

Answer 3

inflammation of the brain tissue with 2 subtypes (infectious and autoimmune)

Question 4

Infectious enceph

Answer 4

caused by viral infection (measles, mumps, herpes, etc)

Question 5

Autoimmune enceph

Answer 5

caused by antibodies/immune system attacking the brain
-causes brain swelling
-progresses over days/week

Question 6

Encephalitis treatments

Answer 6

depends on cause
antivirals
antibacterial
immunotherapy

Question 7

Enceph prognosis

Answer 7

can lead to brain damage
mild: full recovery
mod/severe: permanent cog and physical deficits, death

Question 8

Meningitis

Answer 8

inflammation of fluid and protective layers of meninges of brain and spinal cord
viral: caused by viral infection (most common)
bacterial: bacterial infection
Other: fungal/parasitic/turbulosis

Question 9

Menin treatment

Answer 9

depends on course/symptoms
antiviral and antibacterial

Question 10

Menin prognosis

Answer 10

viral usually mild, full recovery
bacterial 15-20% death

Question 11

Schizophrenia

Answer 11

2+ core features for a sig. period of time during a 1 month period
-continuous signs for 6 months with at least one month of active symptoms
-1% of world pop
-ass with DISC 1 gene

Question 12

Schizo environmental factors

Answer 12

prenatal malnutrition, tobacco use during pregnancy, viral infection during preg, vitamin D def during childhood

Question 13

Positive symptoms

Answer 13

hallucinations, delusions, adding things that normal people dont have.
-overactive mesolimbic dopamine circuits