Epilepsy, concussions, and MS Flashcards
Seizures
brief, sudden, excessive discharge of electrical activity in the brain
Provoked seizure
have a direct cause (head injury, non-epileptic infection, drugs)
Epileptic seizure
does not have an immediate cause
Psychogenic Non-epileptic seizures (PNES)
resemble seizures, but without abnormal brain electrical activity; caused by stress
Focal seizure
onset is localized to a specific region of the brain
Simple seizure
does not impair consciousness
Complex seizure
alters consciousness
Generalized tonic clonic “grand mal” seizure
tonic extension of extremities and trunk (20 seconds) clonic synchronous rhythmic muscle movements (45 seconds)
EEG
measures brain electrical activity to identify seizures
- has poor sensitivity for location, but high specificity for seizures when interictal epileptiform activity is present
epilepsy
a disorder characterized by at least 2 unprovoked seizures 24 hours apart.
-can start @young age or in adulthood
-when starting in adulthood, more PNES
Anti-epileptic drugs (AEDS)
effective in 70% of individuals
-side effects may impact cognition and mood
-if 3 fail, likelihood of control is low (called intractable/refractory epilepsy)
Resection surgery for epilepsy
removal source of seizures
-most common surgery for intractable
-PNES would not improve w/surgery
Disconnection surgery for epilepsy
disrupt pathways allowing seizure to spread
Implantation of medical devices for epilepsy
vagal nerve stimulator (VNS) or deep brain stimulation (DBS)
Status epilepticus
condition in which patient undergoes series of seizures without regaining consciousness
-damage caused by excessive glutamate release during seizure
-seizures last more than 5 mins