Infection And Inflamation Flashcards
Reservoir
Natural habitat of the organism we’re growth and multiplication occur
Prevalent resistant organisms
- methicillin-resistant staphylococcus aureus (MRSA)
- vancomycin resistant enterococcus (VRE)
- aminoglyciside resistance pseudomonas
Inanimate reservoir
Soil, water, other environmental sources, medical equipment
Animate reservoir
People, animals, insects
Portal of exit
- Method for the pathogens to leave the source
- Respiratory tract, gastrointestinal tract, general urinary track, breaks in skin, mucous membranes, blood stream
Laboratory data indicating infection
- Elevated white blood cell count
- increase in specific type of white blood cells
- elevated erythrocyte sedimentation rate
- Presence of pathogen in urine, blood, sputum or draining cultures
Bacteria
Most significant in most prevalent in hospital settings
Virus
Smallest of all micro organisms
Fungi
Plant like organisms present in air, soil and water
Potential to produce disease depends on
- Number of organisms
- virulence ( ability to cause disease or harm)
- Competence of persons immune system
- Length and intimacy of contact between person in microorganism
Chain of infection
Three primary routes:
1) contact
- Direct= “touching the wound”
- indirect= “touching object with it “
2) droplet ( sneeze greater than 5mcm)
3) airborne (breathing, coughing, sneeze, talk less than 5mcm)
Two lesser routes:
- vehicles
- vector
Stages of infection
1) incubation period: organism growing and multiplying, don’t know you have it yet
2) prodromal stage: person is most infectious vague and nonspecific signs of disease, I don’t know you’re sick you just “feel off”
3) full stage of illness: presence of specific signs and symptoms of disease
4) convalescent period: recovery from infection
Body’s defense against infection
- body’s normal flora
- inflammatory response
- immune response
Inflammatory response
Protective mechanism
- localized
- attack
- remove dead damaged tissue
- repair/ replace
Inflammatory response types
1) vascular
- vasoconstriction
• confine to area of injury
• limit tissue damage
- vasodilation
• flood area to promote healing
2) cellular ( most active during first 24h)
- increase cellular permeability
• WBC move info area- clean wound- consume debris in order to heal
• results in pain, edema, loss of function