Important Info 2.4 exam 3

Question 1

Which group is categorized by primary pulmonary HTN (PAH)?

Answer 1

Group 1

Question 2

Which drug has an adverse drug reaction causing hair growth?

Answer 2

Minoxidil

Question 3

What is the mechanism of action for hydralazine?

Answer 3

Action on IP3

Question 4

What drug is associated with purple toe syndrome?

Answer 4

Warfarin

Question 5

Rivaroxaban is monitored using what?
a. aPTT
b. INR
c. PT
d. None of the above

Answer 5

d. None of the above

do NOT require routine monitoring - do require renal dosing

Question 6

What drug has an unique adverse drug reaction causing dyspnea?

Answer 6

Ticagrelor

Question 7

What is alteplase mechanism of action?

Answer 7

Converts plasminogen to plasmin

Question 8

What drug causes inhibition of ADP binding at the P2Y12 receptor?

Answer 8

Cangrelor

Question 9

Which of these is a COX inhibitor?

Answer 9

Aspirin

Question 10

What is the last stage in atherogenesis?

Answer 10

The fibrous cap forms over the lipid core

Question 11

What drug has a mechanism of action that inhibits TRAP?

Answer 11

Vorapaxar

Question 12

Which of these drugs is available as an IV?
a. Epoprostenol
b. Iloprost
c. Treprostinil
d. A and C

Answer 12

d. A and C

Question 13

What drug causes flushing?
a. Bosentan
b. Sildenafil
c. Epoprostenol
d. All of the above

Answer 13

d. All of the above

Question 14

What drug has the highest amount of drug-drug interactions?

Answer 14

Atorvastatin

Question 15

Adverse drug e ects for HMG-CoA reductase inhibitors include
a. Hepatotoxicity
b. Myopathy
c. Memory loss
d. All of the above

Answer 15

d. All of the above

Question 16

What stage does the final common pathway occur?
a. Adhesion
b. Aggregation
c. Activation
d. Fibrosis

Answer 16

b. Aggregation

Question 17

Which of the following lower triglycerides?

Answer 17

Gemfibrozil (all fibrates – look for “fib” in the name)

Question 18

Which of the following drugs causes blocking transport protein NPC1L1?

Answer 18

Ezetimibe

Question 19

Which of the following drugs has an ADR of hyperuricemia?
a. Niacin
b. Bempedoic
c. Cholestyramine
d. A and B

Answer 19

d. A and B

Question 20

Which is the mechanism of action for Colestipol?

Answer 20

Bind to bile in the intestine preventing resorption of bile acid

Question 21

Which of the following drugs causes nasopharyngitis?
a. Evinacumab
b. Lomitapide
c. Inclisiran
d. A and B

Answer 21

d. A and B

Question 22

What drug has an injection site reaction?

Answer 22

Inclisiran

Question 23

What is the “bad cholesterol”?

Answer 23

LDL

Question 24

What drug causes angioedema?
a. Captopril
b. Sacubitril/valsartan
c. Azilsartan
d. A and B

Answer 24

d. A and B

Question 25

46 year old male patient has diabetes mellitus and smokes. How many risk factors for ASCVD does he have?

Answer 25

Three

Question 26

Which of the following factors does Warfarin inhibit? a. Factor III b. Factor VIII c. Factor X d. B and C

Answer 26

d. B and C

Question 27

Which of the following is a PDE5 inhibitor? a. Sildenafil b. Epoprostenol c. Bosentan d. Heparin

Answer 27

a. Sildenafil

Question 28

Which of the following inactivates Factor Xa? a. Tinzaparin b. Apixaban c. Heparin d. All of the above

Answer 28

d. All of the above

Question 29

What is high intensity dosing defined as?

Answer 29

Lowering LDL by greater than or equal to 50%

Question 30

What stage is P2Y12 in?

Answer 30

Activation