Import and Export from the Nucleus

Question 1

The outer nuclear membrane is continuous with the ______.

Answer 1

ER

Question 2

The _____ is continuous with the ER..

Answer 2

outer nuclear envelope

Question 3

The inner nuclear membrane is strengthened by the ____.

Answer 3

nuclear lamina

Question 4

What is the purpose of the nuclear lamina?

Answer 4

strength

Question 5

Where is DNA transcribed?

Answer 5

in the nucleus

Question 6

Where is RNA transcribed?

Answer 6

in the cytoplasm

Question 7

What is imported into the nucleus?

Answer 7

1) polymerases
2) protein kinases/phosphatases
3) histones
4) DNA binding proteins

Question 8

What is exported from the nucleus?

Answer 8

1) ribosomal subunits
2) tRNAs
3) mRNAS

Question 9

How many proteins are there per NPC?

Answer 9

500-1000

Question 10

What does NPC stand for?

Answer 10

nuclear pore complex

Question 11

The nuclear envelope contains macromolecular pores called ____.

Answer 11

nuclear pore complexes (NPCs)

Question 12

30 distinct proteins, called ______, are repetitively arranged in subcomplexes to form the NPCs.

Answer 12

nucleoporins (Nups)

Question 13

______, called nucleoporins (Nups), are repetitively arranged in subcomplexes to form the NPCs.

Answer 13

30 distinct proteins

Question 14

Nups contain about 3500 ___-___ repeats each.

Answer 14

phenylalanine (F), glycine (G)

Question 15

____ contain about 3500 F-G repeats each.

Answer 15

Nups

Question 16

Nups contain about _____ F-G repeats each.

Answer 16

3500

Question 17

What is the purpose of the F-G repeats?

Answer 17

they interact with hydrophobic residues in the pore

Question 18

The pore complex has 3 modes of transport: _____, spontaneous migration, and facilitated transport.

Answer 18

filtered by size

Question 19

The pore complex has 3 modes of transport: filtered by size, spontaneous migration, and _____.

Answer 19

facilitated transport

Question 20

The pore complex has 3 modes of transport: filtered by size, _____, and facilitated transport.

Answer 20

spontaneous migration

Question 21

____ has 3 modes of transport: filtered by size, spontaneous migration, and facilitated transport.

Answer 21

The pore complex

Question 22

What is spontaneous migration?

Answer 22

changing the surface hydrophobicity to allow molecules to traverse the membrane

Question 23

What is facilitated transport?

Answer 23

using carrier molecules to transport cargo molecules