Acids, Bases, and Buffers Flashcards

1
Q

Effective buffering occurs in the range from ____ or within ____ on either side of the pKa.

A

0.1 to 10; one pH unit

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1
Q

The bicarbonate buffer system is effective ____ units above its pKa.

A

1.3

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2
Q

What does Helicobacter pylori do?

A

causes gastric ulcers

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2
Q

A ____ is a mixture of a weak acid (HA) and its conjugate base (A).

A

buffer

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2
Q

The bicarbonate buffer system is the most important regulator of extracellular ___.

A

pH

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2
Q

The _________ is OPEN, modulated by regulation of CO2 loss in the ____ and H+ /HCO3- excretion in the _____.

A

bicarbonate buffer system; lung; kidney

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3
Q

The _____ the pKa, the stronger the base.

A

higher

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4
Q

The bicarbonate buffer system is effective 1.3 units ____ its ____.

A

above; pKa

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5
Q

Effective _____occurs in the range from 0.1 to 10 or within one pH unit on either side of the ____.

A

buffering; pKa

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6
Q

What is the causative agent of gastric ulcers?

A

Helicobacter pylori

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7
Q

The bicarbonate buffer system is OPEN, modulated by regulation of CO2 loss in the lung and _____ excretion in the kidney.

A

H+ /HCO3-

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8
Q

memorize this bicarb equation

A

pH = 6.1 + log 20 = 7.4

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9
Q

A buffer is a mixture of a ____ and _____.

A

weak acid (HA); its conjugate base (A)

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9
Q

The bicarbonate buffer system is ____, modulated by regulation of ____ in the lung and H+ /HCO3- excretion in the kidney.

A

open; CO2 loss

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11
Q

pH = pKa + log([proton acceptor]/[proton donor])

A

the Henderson-Hasselbach equation

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12
Q

The _____ is the most important regulator of extracellular pH.

A

bicarbonate buffer system

14
Q

The higher the pKa, the _____ the base.

A

stronger

16
Q

The _____ the pKa, the stronger the acid.

A

lower

17
Q

pH = 6.1 + log 20 = 7.4

A

memorize this bicarb equation

19
Q

The lower the pKa, the _____ the acid.

A

stronger

20
Q

The modified H-H equation for the bicarbonate system is?

A

pH = 6.1 + log [HCO3-]mM/ .03Pco2mmHg

21
Q

What is the Henderson-Hasselbach equation?

A

pH = pKa + log([proton acceptor]/[proton donor])

22
Q

How does Helicobacter pylori cause gastric ulcers?

A

by using urease to create a neutral pH environment

23
Q

The higher the ____, the stronger the base.

A

pKa

24
Q

____ acids and bases are reversibly protonated and deprotonated.

A

Weak

26
Q

Weak acids and bases are _____ and deprotonated.

A

reversibly protonated

27
Q

The _____ is effective 1.3 units above its pKa.

A

bicarbonate buffer system

28
Q

The lower the ____, the stronger the acid.

A

pKa