Composition of Cells Flashcards

1
Q

_________ are composed of lipids.

A

Membranes

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2
Q

The two major fluid compartments are the _____ and _____.

A

intracellular; extracellular

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3
Q

Where is the concentration of Na+ higher?

A

in the ECF

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3
Q

Where is the concentration of water higher?

A

it’s the same in the ICF and ECF

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4
Q

Membranes are composed of _____.

A

lipids

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5
Q

What are the principal inorganic ions in the cell?

A

Na+, K+, and Cl-

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6
Q

Name the 5 components of ICF or ECF.

A

1) Na+ 2) K+ 3) Cl- 4) proteins 5) water

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7
Q

The excess anions create an _______ potential difference between the inside and the outside of the cell, called the ______.

A

electrical; membrane potential

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7
Q

Stimuli for gated channels include _____, ______, ______, or _______,

A

1) electricity (voltage gated) 2) mechanical 3) chemicals 4) temperature

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8
Q

What components can pass through the membrane?

A

K+, Cl-, H2O

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9
Q

It is estimated that 50% of the energy we expend at rest is used to _____.

A

pump ions across membranes

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10
Q

What is an example of a primary active transporter?

A

the Na+/Cl- pump

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11
Q

The ability of the membrane to withstand the imposed electric force with a strength of about 100,000 volts/cm is due to its __________.

A

lipid composition

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12
Q

Channels behave as _____ or _____ in the membrane.

A

passive pores; tunnels

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13
Q

What is the intracellular fluid comprised of?

A

mitochondrial, vesicular, nuclear, and other subcompartments

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14
Q

The patch clamp technique allows one to see ______.

A

individual ion channels at work

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14
Q

If the energy for transport comes directly from metabolism (usually splitting ATP), the transport is called _________. transport.

A

primary active

15
Q

Some channels contain molecular ______.

16
Q

Where is the concentration of K+ higher?

A

in the ICF

16
Q

______ work thousands of times slower than channels.

A

Transporters

17
Q

Some charged/polar substances cross membranes by passing through _____, which behave as passive pores, or tunnels, in the membrane.

18
Q

Some substances cross membranes by binding to _____ and being escorted (‘carried’) across.

19
Q

Transporters are also needed in order to _____ to concentrate them on one side against ______.

A

pump molecules across a membrane; their energy gradient

20
Q

If the transport energy comes from other sources and not ATP, it is called ______.

A

secondary active transport

21
If 2% of K+ leaks out of the cells, \_\_\_\_\_\_\_.
the pt can die
22
How is the patch clamp technique performed?
A glass pipette touches a cell - gentle suction draws membrane into the mouth of the pipette to form a seal- channel gate opens- record the electric current through the channel
23
What is the extracellular fluid comprised of?
1) plasma 2) lymph 3) interstitial fluid
24
The ability of the membrane to withstand the imposed electric force with a strength of about ________ is due to its lipid composition.
100,000 volts/cm
25
What is the total volume of the extracellular fluid?
13 liters
27
What is the boundary btw the intra- and extracellular fluids?
the plasma membrane
28
The excess ____ create an electrical potential difference between the inside and the outside of the cell, called the membrane potential.
anions
30
Where is the concentration of Cl- higher?
in the ECF
31
The cytoplasm of nearly all cells is electrically \_\_\_\_\_compared to the ECF.
negative
33
Cells contain a few more _____ ions than _____ ions.
negative; positive
34
Most channels are _______ for particular ions.
selective
35
What is the total volume of the intracellular fluid?
27 liters
36
It is estimated that ____ of the energy we expend at rest is used to pump ions across membranes.
50%
37
Name 2 general kinds of proteins that mediate transmembrane movement of charged substances.
1) channels 2) transporters
39
Secondary active transport also depends on \_\_\_\_\_\_.
metabolism
40
Where is the concentration of protein higher?
in the ICF