immunology

Question 1

cytokines produced by macrophages

Answer 1

IL1, IL6, IL8, IL12, TNFa

Question 2

cytokines produced by all T cells

Answer 2

IL2 and IL3

Question 3

cytokine that stimulates TH1 cells

Answer 3

IL12

Question 4

cytokines produced by TH1 cells

Answer 4

Interferon - gamma

Question 5

cytokines produced by TH2 cells

Answer 5

IL4, IL5, IL10

Question 6

cytokines that inhibit the immune response

Answer 6

TGF-B and IL10

Question 7

major chemotactic factor for neutrophils

Answer 7

IL8

Question 8

IL2

Answer 8

produced almost exclusively by T lymphocytes and function to stimulate the growth and differentiation of T cells, B cells, NK cells and macrophages; IL2 binds to IL2R of T cells for autocrine clonal proliferation

Question 9

cytokine induced T cell proliferation

Answer 9

IL2 and IL2R expression on T cells, autocrine fashion for clonal proliferation

Question 10

TNF-a

Answer 10

primarily produced by activated macrophages; induces systemic inflammatory response and in high concentrations, causes sx of septic shock and cachexia

Question 11

INF-a functions

Answer 11

mostly anti-viral

Question 12

GM-CSF function

Answer 12

stimulates stem cell production of granulocytes and monocytes