HY - anatomy + embyrology Flashcards
polyhydraminos + elevated AFP
anencephaly - cannot swallow amniotic fluid due to brain damage
holoprosencephaly
no midline separation of hemispheres + cyclopia and cleft lip/palate + fetal alcohol syndrome
error in neuronal migration leading to smooth brain
lissencepahly
tonsilar herniation + aqueductal stenosis + hydrocephaly
Chiari II malformation
large posterior fossa + absent cerebellar vermis + enlargement 4th ventricle
Dandy-Walker Syndrome
loss of pain + temperature in upper extremities and preserved touch
syringomyelia; spinothalamic tract lost first
failure of spinal canal closure at week 4
neural tube defect due to folate deficiency or teratogen (valproic acid)
elevated AFP + elevated AFP and acetylcholinesterase in CSF
NT defect
cerebrospinal fluid-filled meningeal tissue that has herniated through vertebral defect + intact movements in baby
meningocele
1st cleft
external auditory meatus
remnant 2-4 clefts
persistent cervical sinus on lateral neck
1st pouch
middle ear, eustachian tube, mastoid air cells
2nd pouch
epithelium of palatine tonsil
3rd pouch
inferior parathyroids , thymus
4th pouch
superior parathyroids
from which pouch is inferior parathyroid derived from?
3rd
midline cyst that moves with swallowing
thyroglossal duct cyst due to failed migration of thyroid from tongue down neck
mandibular hypoplasia + fascial abnormalities (cleft lip etc)
first pharyngeal arch
maxillary artery from where?
1st aortic arch
stapedial artery from where?
2nd aortic arch
carotid arteries from where?
3rd aortic arch
right subclavian + some aortic arch from where?
4th aortic arch
proximal pulmonary arteries from where?
6th aortic arch
patient comes in with carotid bruits. embryonic origin of this structure?
third aortic arch
patient has giant cell arteritis with jaw claudication. what is the embryonic origin of this structure?
first aortic arch
structures of foregut
pharynx to duodenum; blood suplly by celiac artery
structures of midgut
duodenum to transverse colon; blood supply is SMA
structures of hindgut
transverse colon to rectum; blood supply is IMA
what is embryonic origin and blood supply of the stomach?
foregut and celiac artery
what it is the embryonic origin and blood supply of sigmoid rectum?
hindgut and IMA
what is the embryonic origin and blood supply of terminal ileum?
midgut and SMA
ventral pancreas rotates in front of the gut instead of behind
annular pancreas
olive-sized, solid mass in stomach of newborns
pyloric stenosis; delayed or absent gastric emptying with non-billious vomit
how do you differentiate projectile vomiting of newborn?
billious = annular pancreas; non-bilious = pyloric stenosis
embryonic origin and blood supply of structure involved in non-billous projectile vomiting of newborn?
pyloric stenosis of stomach = foregut and celiac artery
3 beginning parts of kidney?
pronephros, mesonephros, metanephros
what comprises metanephros and what does each make?
ureteric bud = ureter, pelvises, calyces, collecting duct; metanephric mesenchyme = kidneys
what is the embryological origin of the kidneys?
metanephric mesenchyme of metanephros
which structure is the last to canalize in kidney development leading to hydronephrosis?
ureteropelvic junction
delayed opening of ureteropelvic junction can lead to _____
hydropheprhosis of baby in utero or newboard
ablation of this structure would inhibit development of the definitive kidney
metanephric duct/ureteric bud of metanephros
newborn with pulmonary hypoplasia + fascial abnormalities most likely had damage to which structure during development?
potter sequence due to failure of kidney development = ureteric bud
what abdominal muscle comprises cremasteric muscle?
internal oblique
what abdominal muscle comprise external spermatic fascia
external oblique
internal oblique = ?
cremasteric muscle
external oblique = ?
external spermatic fascia
transversalis fascia = ?
internal spermatic fascia
what structure must fuse to close connection between periotoneal cavity and scrotum
processus vaginalis
newborn has fluid in scrotum. what embryological development failed?
patient has incomplete fusion of processus vaginalis
meckels diverticulum is remnant of what?
vitelline duct
this embryological remnant in the GI can sometimes have ectopic gastric tissue
meckels diverticulum
intestinal discharge through umbilicus
persistent vitelline duct connecting umbiliculs to intestine contents
what syndrome is associated with the double bubble sign?
duodenal atresia; downs syndrome
projectile non-billious vomiting
pyloric hypertrophy; palpable mass in stomach in newborn
embryology and blood supply of spleen
part of foregut; celiac artery; mesoderm
this structure is a communication point between less and greater sacs
epiploic foramen
above pectinate line, what is lymph drainage, blood flow, blood drainage?
internal iliac nodes, superior rectal artery of IMA, portal vein (can become engorged in portal HTN)
below pectinate line, what is lymph drainage, blood flow, blood drainage?
superficial inguinal nodes, inferior rectal artery from pudendal and internal iliac, IVC
what two structures meet to form anus?
hind gut and ectoderm
vessel involvement with posterior duodenal ulcer
gastroduodenal artery
blood supply of cardia and fundus of stomach
short gastric arteries off of splenic artery
surgeon clamps hepatoduodenal ligament to stop hemorrhage. what vessel are being occluded?
proper hepatic artery, portal vein, cystic duct
the middle colic, right coli, ileocolic, and ileal and jejunal arteries are all branches of what?
SMA
with massive weightloss the last third of the duodenum can become compressed by which vessel?
SMA
watershed areas of colon susceptible to ischemia in times of hypotension
splenic flexure + rectosigmoid junction
which nerve plexus lives in the submucosal layer and absence of this correlates with what disease?
Meissner plexus, absence = hirschprung disease
this muscular nerve plexus is compromised in achalasia
auerbach plexus
columnar epithelium is found in which portion of GI tract
stomach, and distal third of esophagus in cases of barrett’s esophagus
role of brunner’s gland
alkalize acidic contents coming form stomach
what does portal vein carry?
deoxygenated nutrient rich blood from GI
apart from the tail, where does the pancreas lay in the body?
retroperitoneal
borders of hesselbachs triangle
inguinal ligament, inferior epigastrics, rectus abdominis
this weakens making direct hernias possible
transversalis fascia