anti-arryhthmics Flashcards

1
Q

Class IA anti-arrhythmics

A

Procainamide, Quinidine, Disopyramide

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2
Q

Class IB anti-arrhythmics

A

Lidocaine, Phenytoin, Mexiletine

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3
Q

Class IC anti-arrhythmics

A

Flecamide, Propafenone

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4
Q

Class III anti-arrhythmics

A

Sotalol, Amiodarone, Ibutilide, Dofetilide

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5
Q

Class II anti-arrhythmics

A

beta blockers

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6
Q

Class IV anti-arrhythmics

A

nondihydropiridone Ca channel blockers; verapamil + diltiazem

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7
Q

Extras

A

Digoxin, Magnesium, Adenosine, Ivabradine

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8
Q

Cause QT prolongation and risk of Torsades

A

Ia and III

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9
Q

Which QT prolonging drug doesn’t run risk of Torsades

A

Amiodarone

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10
Q

Which act on cardiac myocyte AP?

A

I and III

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11
Q

Which have effect of K+ of myocyte AP?

A

III and Ia

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12
Q

SE of adenosine

A

flushing, hypotension, CP, bronchospasm, feeling of doom

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13
Q

What is responsible for maintaining the electrochemical gradient at resting membrane potential?

A

Na/K ATPase

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14
Q

Ion responsible for node repolarization?

A

K

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15
Q

location of SA node

A

R atria

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16
Q

magnesium is used to treat what specific type of arrhythmia?

A

Torsades De Pointes

17
Q

flushing, chest pain, dyspnea, hypotension

A

Adenosine SE

18
Q

Which class Ia also blocks a -adrenergic and muscarinic receptors, thereby potentially leading to increased heart rate and AV conduction

A

quinidine

19
Q

procainamide SE

A

lupus, N/V/D, agranulocytosis, thrombocytopenia

20
Q

disopyramide SE

A

anticholinergic = urinary retention, dry eyes and mouth, blurred vision, constipation, sedation

21
Q

what two antiarrhytmics can cause pulmonary fibrosis

A

tocainide + amiodarone